Evidence map›Paper›PMID 29936578›Full record

ArticleJournal of industrial microbiology & biotechnology2018

Overexpression of SNF4 and deletions of REG1- and REG2-enhanced maltose metabolism and leavening ability of baker's yeast in lean dough.

Xue Lin, Cui-Ying Zhang, Lu Meng, Xiao-Wen Bai, Dong-Guang Xiao

Abstract read
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In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xue LinCollege of Food Science and Technology, Hainan University, Haikou, 570228, People's Republic of China.
Cui-Ying ZhangTianjin Industrial Microbiology Key Laboratory, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China. cyzhangcy@tust.edu.cn.
Lu MengCollege of Food Science and Technology, Hainan University, Haikou, 570228, People's Republic of China.
Xiao-Wen BaiTianjin Industrial Microbiology Key Laboratory, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
Dong-Guang XiaoTianjin Industrial Microbiology Key Laboratory, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China. xdg@tust.edu.cn.
Tianjin University of Science and Technology · CNHainan University · CN

Funding

the National Natural Science Foundation of China 31171730the Scientific Research Foundation of Hainan University KYQD1660
6 · The paper itself

Abstract

Maltose metabolism of baker's yeast (Saccharomyces cerevisiae) in lean dough is suppressed by the glucose effect, which negatively affects dough fermentation. In this study, differences and interactions among SNF4 (encoding for the regulatory subunit of Snf1 kinase) overexpression and REG1 and REG2 (which encodes for the regulatory subunits of the type I protein phosphatase) deletions in maltose metabolism of baker's yeast were investigated using various mutants. Results revealed that SNF4 overexpression and REG1 and REG2 deletions effectively alleviated glucose repression at different levels, thereby enhancing maltose metabolism and leavening ability to varying degrees. SNF4 overexpression combined with REG1/REG2 deletions further enhanced the increases in glucose derepression and maltose metabolism. The overexpressed SNF4 with deleted REG1 and REG2 mutant ΔREG1ΔREG2 + SNF4 displayed the highest maltose metabolism and strongest leavening ability under the test conditions. Such baker's yeast strains had excellent potential applications.

Indexed as

Gene Deletionalpha-GlucosidasesAMP-Activated Protein KinasesCarrier ProteinsFermentationGene Expression Regulation, FungalGlucoseMaltoseMonosaccharide Transport ProteinsProtein Phosphatase 1Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSymportersTranscription Factorsalpha-GlucosidasesAMP-Activated Protein KinasesCarrier ProteinsGlucoseMAL62 protein, S cerevisiaeMaltosemaltose transport system, S cerevisiaeMonosaccharide Transport ProteinsProtein Phosphatase 1REG1 protein, S cerevisiaeReg2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSNF4 protein, S cerevisiaeSymportersTranscription FactorsBaker’s yeastGlucose repressionMaltose metabolismRegulator

Identifiers

PMID29936578
OpenAlexW2810293717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.