Evidence map›Paper›PMID 29936461›Full record

ArticleIn vivo (Athens, Greece)

Accelerated Wound Healing on the Skin Using a Film Dressing with β-Glucan Paramylon.

Kosuke Yasuda, Misa Ogushi, Ayaka Nakashima, Yoshihisa Nakano, Kengo Suzuki

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  10. Review
  11. Life (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Enhancing of Wound Healing in Burn Patients throughJournal of fungi (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Frontiers in bioengineering and biotechnology · 2021
    Article
  16. Nutrients · 2020
    Article
  17. Genetic Engineering Strategies forFrontiers in bioengineering and biotechnology · 2020
    Review
  18. Article
  19. Bioproducts FromFrontiers in bioengineering and biotechnology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kosuke Yasudaeuglena Co., Ltd., Tokyo, Japan.
Misa OgushiOsaka Prefecture University, Osaka, Japan.
Ayaka Nakashimaeuglena Co., Ltd., Tokyo, Japan.
Yoshihisa NakanoOsaka Prefecture University, Osaka, Japan.
Kengo Suzukieuglena Co., Ltd., Tokyo, Japan suzuki@euglena.jp.
Osaka Prefecture University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimβ-Glucan has been shown to modulate immune system and potentially aid wound healing. A naturally-available β-glucan, paramylon, is available in the form of a film, which would be an ideal form to use in wound care. The aim of this study was to examine the therapeutic efficacy of paramylon film as a wound dressing. MATERIALS AND

methodsAn acute wound was created on the skin of the posterior aspect of mice and wound healing was observed for 5 days. Mice were treated with either paramylon film or conventional cellulose film.

resultsThe time course of changes in wound size revealed that paramylon film dressing application leads to significantly faster wound contraction than conventional cellulose film. The dressing suppressed elevation of the inflammatory cytokines interferon gamma, interleukin-6, and vascular endothelial growth factor.

conclusionβ-Glucan paramylon film can facilitate wound healing by inhibiting inflammatory aggression and has potential application as a novel wound dressing.

Indexed as

Wound HealingAnimalsBandagesbeta-GlucansGlucansHumansMiceSkinbeta-GlucansGlucansparamyloncytokineparamylonwound dressingβ-glucan

Identifiers

PMID29936461
PMCPMC6117762
OpenAlexW2810631495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.