Evidence map›Paper›PMID 29936288›Full record

ArticleEnvironmental research2018

Unconventional natural gas development and pediatric asthma hospitalizations in Pennsylvania.

Mary D Willis, Todd A Jusko, Jill S Halterman, Elaine L Hill

Abstract read
In one paragraph

Article in Environmental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Impact of oil and gas boom and busts on working-age mortality in the U.S.Environmental epidemiology (Philadelphia, Pa.) · 2025
    Article
  6. Review
  7. Sociodemographic and Population Exposure to Upstream Oil and Gas Operations in Canada.International journal of environmental research and public health · 2024
    Article
  8. Article
  9. The human health effects of unconventional oil and gas development (UOGD): A scoping review of epidemiologic studies.Canadian journal of public health = Revue canadienne de sante publique · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mary D WillisSchool of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
Todd A JuskoDepartment of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Jill S HaltermanDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Elaine L HillSchool of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA; Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Electronic address: elaine_hill@urmc.rochester.edu.

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
The Health Consequences of Shale Gas DevelopmentDP5OD021338 · OD · UNIVERSITY OF ROCHESTER · PI HILL, ELAINE L · 2015 to 2019
$1.9M
NIEHS NIH HHS L40 ES027225NIEHS NIH HHS P30 ES001247NIH HHS DP5 OD021338
6 · The paper itself

Abstract

backgroundPediatric asthma is a common chronic condition that can be exacerbated by environmental exposures, and unconventional natural gas development (UNGD) has been associated with decreased community air quality. This study aims to quantify the association between UNGD and pediatric asthma hospitalizations.

methodsWe compare pediatric asthma hospitalizations among zip codes with and without exposure to UNGD between 2003 and 2014 using a difference-in-differences panel analysis. Our UNGD exposure metrics include cumulative and contemporaneous drilling as well as reported air emissions by site.

resultsWe observed consistently elevated odds of hospitalizations in the top tertile of pediatric patients exposed to unconventional drilling compared with their unexposed peers. During the same quarter a well was drilled, we find a 25% increase (95% CI: 1.07, 1.47) in the odds of being hospitalized for asthma. Ever-establishment of an UNGD well within a zip code was associated with a 1.19 (95% CI: 1.04, 1.36) increased odds of a pediatric asthma hospitalization. Our results further demonstrate that increasing specific air emissions from UNGD sites are associated with increased risks of pediatric asthma hospitalizations (e.g. 2,2,4-trimethylpentane, formaldehyde, x-hexane). These results hold across multiple age groups and sensitivity analyses.

conclusionsCommunity-level UNGD exposure metrics were associated with increased odds of pediatric asthma-related hospitalization among young children and adolescents. This study provides evidence that additional regulations may be necessary to protect children's respiratory health from UNGD activities.

Indexed as

AdolescentAir PollutantsAsthmaChildChild, PreschoolEnvironmental ExposureFemaleHospitalizationHumansMaleNatural GasPennsylvaniaAir PollutantsNatural GasAir pollutionEnvironmental healthIndustrial emissionsPediatric asthmaUnconventional natural gas development

Identifiers

PMID29936288
PMCPMC6110967

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.