Evidence map›Paper›PMID 29936077›Full record

ReviewTranslational research : the journal of laboratory and clinical medicine2018

Liquid biopsy approach in the management of prostate cancer.

Irbaz Bin Riaz, Liang Wang, Manish Kohli

Abstract readReview
In one paragraph

Review in Translational research : the journal of laboratory and clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Glycans as Biomarkers in Prostate Cancer.International journal of molecular sciences · 2019
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irbaz Bin RiazDepartment of Oncology, Mayo Clinic, Rochester, Minnesota.
Liang WangDepartment of Pathology and MCW Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: liwang@mcw.edu.
Manish KohliDepartment of Oncology, Mayo Clinic, Rochester, Minnesota. Electronic address: kohli.manish@mayo.edu.

Funding

Cell free nucleic acid-based biomarkers in advanced prostate cancerR01CA212097 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI KOHLI, MANISH, WANG, LIANG · 2017 to 2022
$3.1M
NCI NIH HHS R01 CA212097
6 · The paper itself

Abstract

Liquid biopsies examine tumor cells or tumor genomic content in circulating fluids. In advanced prostate cancer which metastasizes frequently to the bone, it is difficult to evaluate underlying and evolving genomic heterogeneity of skeletal metastases for effecting clinical care for which reason liquid biopsies offer an alternate approach. In this review, we will summarize the current state of a wide variety of liquid biopsy-based biomarker assays currently being investigated and developed for managing prostate cancer. We will also highlight technical and clinical challenges and opportunities for translating liquid biopsies into clinical applications.

Indexed as

BiomarkersCell-Free Nucleic AcidsHumansLiquid BiopsyMaleNeoplasm StagingNeoplastic Cells, CirculatingProstatic NeoplasmsBiomarkersCell-Free Nucleic Acids

Identifiers

PMID29936077
PMCPMC6631037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.