Evidence map›Paper›PMID 29935979›Full record

SynthesisClinical psychology review2018

Treatment of depression, anxiety, and trauma-related disorders during the perinatal period: A systematic review.

Yael I Nillni, Aydan Mehralizade, Laura Mayer, Snezana Milanovic

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical psychology review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06597448 (Public Health Nurse-Peer Co-Delivered Group Cognitive Behavioral Therapy for Postpartum Depression), which is not on this map. Cited by 95 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 18 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06597448 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Public Health Nurse-Peer Co-Delivered Group Cognitive Behavioral Therapy for Postpartum Depression: A Randomized Controlled Trial

TypeinterventionalSponsorMcMaster UniversityRan2024 to 2028Enrolled170ConditionsPostpartum DepressionArmsCognitive Behavioral Therapy for Postpartum Depression (PPD)
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 18 syntheses or guidelines pooled it, 202 citations in OpenAlex.

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  17. Interpersonal Psychotherapy to Reduce Psychological Distress in Perinatal Women: A Systematic Review.International journal of environmental research and public health · 2020
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yael I NillniNational Center for PTSD, Women's Health Sciences Division at VA Boston Healthcare System, United States; Department of Psychiatry, Boston University School of Medicine, United States. Electronic address: ynillni@bu.edu.
Aydan MehralizadeBoston Medical Center, United States.
Laura MayerDepartment of Psychiatry, Boston University School of Medicine, United States.
Snezana MilanovicDepartment of Psychiatry, Boston University School of Medicine, United States.
Boston University · USBoston Medical Center · US

Funding

PTSD-Related Neurobiological Mediators of Negative Pregnancy OutcomesK23HD087428 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NILLNI, YAEL I · 2017 to 2020
$616k
NICHD NIH HHS K23 HD087428
6 · The paper itself

Abstract

Women with psychiatric disorders during pregnancy and the postpartum period (i.e., perinatal period) are at increased risk for adverse maternal and child outcomes. Effective treatment of psychiatric disorders during the perinatal period is imperative. This review summarizes the outcomes of 78 studies focused on the treatment of depression, anxiety, and trauma-related disorders during the perinatal period. The majority of studies focused on perinatal depression (n = 73). Of the five studies focused on anxiety or trauma-related disorders, only one was a randomized controlled trial (RCT). The most studied treatment was cognitive behavioral therapy (CBT; n = 22), followed by interpersonal psychotherapy (IPT; n = 13). Other interventions reviewed include other talk therapies (n = 5), collaborative care models (n = 2), complementary and alternative medicine approaches (n = 18), light therapy (n = 3), brain stimulation (n = 2), and psychopharmacological interventions (n = 13). Eleven studies focused specifically on treatment for low-income and/or minority women. Both CBT and IPT demonstrated a significant benefit over control conditions. However, findings were mixed when these interventions were examined in low-income and/or minority samples. There is some support for complementary and alternative medicine approaches (e.g., exercise). Although scarce, SSRIs demonstrated good efficacy when compared to a placebo. However, SSRIs did not outperform another active treatment condition (e.g., CBT). There is a tremendous need for more studies focused on treatment of perinatal anxiety and trauma-related disorders, as well as psychopharmacological effectiveness studies. Limitations and future directions of perinatal treatment research, particularly among low-income and/or minority populations, are discussed.

Indexed as

Anxiety DisordersComplementary TherapiesDepressive DisorderFemaleHumansPregnancyPregnancy ComplicationsPsychotherapyTrauma and Stressor Related DisordersAnxietyDepressionPostpartumPosttraumatic stress disorderPregnancyTreatment

Identifiers

PMID29935979
PMCPMC6637409
OpenAlexW2807198361

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.