Evidence map›Paper›PMID 29935051›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2019

Who can tolerate a marginal kidney? Predicting survival after deceased donor kidney transplant by donor-recipient combination.

Sunjae Bae, Allan B Massie, Alvin G Thomas, Gahyun Bahn, Xun Luo, Kyle R Jackson, Shane E Ottmann, Daniel C Brennan, Niraj M Desai, Josef Coresh and 2 more

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Using Information Available at the Time of Donor Offer to Predict Kidney Transplant Survival Outcomes: A Systematic Review of Prediction Models.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Pooled it
  2. Article
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  7. Review
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  10. Article
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  13. Assessing Deceased-Donor Kidneys Through Posttransplant Survival Prediction Algorithms.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Decreasing efficiency in deceased donor kidney offer notifications under the new distance-based kidney allocation system.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  19. Article
  20. The dynamics of deceased donor kidney transplant decision making: insights from studying individual clinicians' offer decisions.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sunjae BaeDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-0098-8816
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alvin G ThomasDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-4911-8192
Gahyun BahnDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Xun LuoDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kyle R JacksonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Shane E OttmannDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Daniel C BrennanDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Niraj M DesaiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jacqueline M Garonzik WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
Mogam Science Scholarship FoundationNIDDK NIH HHS K23 DK115908NIDDK NIH HHS K24 DK101828
6 · The paper itself

Abstract

The impact of donor quality on post-kidney transplant (KT) survival may vary by candidate condition. Characterizing this variation would increase access to KT without sacrificing outcomes. We developed a tool to estimate post-KT survival for combinations of donor quality and candidate condition. We studied deceased donor KT recipients (n = 120 818) and waitlisted candidates (n = 376 272) between 2005 and 2016 by using the Scientific Registry of Transplant Recipients. Donor quality and candidate condition were measured by using the Kidney Donor Profile Index (KDPI) and the Estimated Post Transplant Survival (EPTS) score. We estimated 5-year post-KT survival based on combinations of KDPI and EPTS score using random forest algorithms and waitlist survival by EPTS score using Weibull regressions. Survival benefit was defined as absolute reduction in mortality risk with KT. For candidates with an EPTS score of 80, 5-year waitlist survival was 47.6%, and 5-year post-KT survival was 78.9% after receiving kidneys with a KDPI of 20 and was 70.7% after receiving kidneys with a KDPI of 80. The impact of KDPI on survival benefit varied greatly by EPTS score. For candidates with low EPTS scores (eg, <40), the KDPI had limited impact on survival benefit. For candidates with middle or high EPTS scores (eg, >40), survival benefit decreased with higher KDPI but was still substantial even with a KDPI of 100 (>16 percentage points). Our prediction tool (www.transplantmodels.com/kdpi-epts) can support individualized decision-making on kidney offers in clinical practice.

Indexed as

Donor SelectionAdultFemaleFollow-Up StudiesHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPrognosisRegistriesSurvival RateTissue and Organ ProcurementTissue DonorsTransplant RecipientsWaiting Listsclinical decision-makingclinical research/practiceepidemiologykidney transplantation/nephrologyorgan acceptanceregistry/registry analysis

Identifiers

PMID29935051
PMCPMC6309666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.