Evidence map›Paper›PMID 29935042›Full record

ArticleCellular microbiology2019

A pleiotropic role of FlaG in regulating the cell morphogenesis and flagellar homeostasis at the cell poles of Treponema denticola.

Kurni Kurniyati, Jun Liu, Jing-Ren Zhang, Yunjiang Min, Chunhao Li

Open access · greenAbstract read
In one paragraph

Article in Cellular microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. FlaG competes with FliS-flagellin complexes for access to FlhA in the flagellar T3SS to controlProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Motility inMicroorganisms · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Kurni KurniyatiPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, Virginia, USA.
Jun LiuDepartment of Microbial Pathogenesis & Microbial Sciences Institute, Yale School of Medicine, New Haven, Connecticut, USA.
Jing-Ren ZhangCenter for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China.
Yunjiang MinSchool of Biological and Pharmaceutical Engineering, West Anhui University, Lu'an, China.
Chunhao LiPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-1872-4870
Virginia Commonwealth University · USMicrobial ID (United States) · USTsinghua University · CNWest Anhui University · CN

Funding

Structure-Function Relationships in the Spirochetal Flagellar MotorR01AI087946 · NIAID · YALE UNIVERSITY · PI LIU, JUN · 2010 to 2025
$6.6M
Understanding Unique Aspects of Motility and Chemotaxis in Borrelia burgdorferiR01AI078958 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI Chunhao Chris Li · 2008 to 2026
$5.7M
Exploring New Virulence Factors of the Oral Spirochete Treponema denticolaR01DE023080 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI Chunhao Chris Li · 2013 to 2026
$5.2M
NIAID NIH HHS R01 AI078958NIAID NIH HHS R01 AI087946NIDCR NIH HHS R01 DE023080
6 · The paper itself

Abstract

FlaG homologue has been found in several bacteria including spirochetes; however, its function is poorly characterised. In this report, we investigated the role of TDE1473, a putative FlaG, in the spirochete Treponema denticola, a keystone pathogen of periodontitis. TDE1473 resides in a large gene operon that is controlled by a σ

Indexed as

Amino Acid SequenceBacterial ProteinsFlagellaPeriodontitisPromoter Regions, GeneticTreponema denticolaBacterial ProteinsFlaGflagellamotilityspirocheteTreponema denticola

Identifiers

PMID29935042
PMCPMC6309649
OpenAlexW2810002075

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.