Evidence map›Paper›PMID 29934812›Full record

ArticleGenes & genomics2018

Differential expression of primary pair-rule genes during bidirectional regeneration in Perionyx excavatus.

Yun-Sang Yu, Jin-Se Kim, Brenda Irene Medina Jiménez, Tae-Wuk Kim, Sung-Jin Cho

Abstract read
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In one paragraph

Article in Genes & genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yun-Sang YuSchool of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 361-763, Republic of Korea.
Jin-Se KimSchool of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 361-763, Republic of Korea.
Brenda Irene Medina JiménezSchool of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 361-763, Republic of Korea.
Tae-Wuk KimDepartment of Life Sciences, Hanyang University, Seoul, 133-791, Republic of Korea. twgibio@hanyang.ac.kr.
Sung-Jin ChoSchool of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 361-763, Republic of Korea. sjchobio@chungbuk.ac.kr.
Chungbuk National University · KRHanyang University · KR

Funding

Hanyang University HY-2011-NRural Development Administration CABX, No. PJ010001
6 · The paper itself

Abstract

The earthworm Perionyx excavatus is a species highly capable of bidirectional regeneration. Pair-rule genes are thought to have an ancestral function in arthropod segmentation. However, orthologs in annelids (i.e. Capitella teleta) do not exhibit segmental expression in the ectoderm or mesoderm. Their role in regeneration is currently unclear. Here, we report the expression profile of primary pair-rule genes (Pex-EvxA, Pex-EvxB, Pex-RuntA, Pex-RuntB, Pex-Hes1A, Pex-Hes1B, Pex-Hes4A, and Pex-Hey) found in P. excavatus using semi-quantitative reverse transcription-polymerase chain reaction. Our results indicated these genes showed variable expression during bidirectional regeneration. Six of these genes might play diverse and potentially critical roles in head and/or tail regeneration.

Indexed as

Amino Acid SequenceAnimalsBody PatterningConservation of Natural ResourcesEctodermGene Expression Regulation, DevelopmentalOligochaetaRegenerationBidirectional regenerationEarthwormPair-rule genesPerionyx excavatus

Identifiers

PMID29934812
OpenAlexW2796242605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.