ArticleInternational orthopaedics2019
Mechanical solutions to salvage failed distraction osteogenesis in large bone defect management.
Article in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tibial bone transport using external fixation in adults: a systematic review.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Corrective Osteotomy after Gradual Lengthening of the Forearm in Children/Adolescents.Journal of wrist surgery · 2026Article
- Gelatin macromolecular microspheres constructed by microfluidics regulate the TNF/HIF-1 signaling axis to reshape the bone immune microenvironment and enhance infectious bone defect repair.Materials today. Bio · 2026Article
- Icariin-loaded GelMa hydrogel encapsulated potassium sodium niobate biomimetic piezoelectric scaffold regulates macrophage polarization to accelerate bone defect repair.Materials today. Bio · 2025Article
- Open segmental tibial bone defects treated with Ilizarov frame: a radiological and functional outcome study with average ten year follow-up.International orthopaedics · 2024Article
- Limb salvage and functional recovery in infected nonunion of the distal tibia treated with the Ilizarov techniques.Journal of clinical orthopaedics and trauma · 2023Article
- The accordion technique enhances bone regeneration via angiogenesis factor in a rat distraction osteogenesis model.Frontiers in physiology · 2023Article
- Rat bone marrow mesenchymal stem cells induced by rrPDGF-BB promotes bone regeneration during distraction osteogenesis.Frontiers in bioengineering and biotechnology · 2023Article
- Mesenchymal Stem Cells-Hydrogel Microspheres System for Bone Regeneration in Calvarial Defects.Gels (Basel, Switzerland) · 2022Article
- Efficacy comparison of trifocal bone transport using unilateral external fixator for femoral and tibial bone defects caused by infection.BMC surgery · 2022Article
- Evaluation of complications associated with bifocal bone transport as treatment for either proximal, intermediate or distal femoral defects caused by infection: outcome analysis of 76 patients.BMC musculoskeletal disorders · 2022Article
- International recognition of the Ilizarov bone reconstruction techniques: Current practice and research (dedicated to 100World journal of orthopedics · 2021Review
- Management of segmental bone defects of the upper limb: a scoping review with data synthesis to inform decision making.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021Article
- Treatment of diaphyseal forearm defects caused by infection using Ilizarov segmental bone transport technique.BMC musculoskeletal disorders · 2021Article
- Interleukin-4-loaded hydrogel scaffold regulates macrophages polarization to promote bone mesenchymal stem cells osteogenic differentiation via TGF-β1/Smad pathway for repair of bone defect.Cell proliferation · 2020Article
- Role of the Ilizarov non-free bone plasty in the management of long bone defects and nonunion: Problems solved and unsolved.World journal of orthopedics · 2020Article
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2 authors.
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Abstract
introductionIlizarov bone transport for large bone defect is challenging and may end in distraction osteogenesis failure. MATERIAL AND
methodsTen forearm and seven tibial defect cases with failed regeneration due to ischaemia during bone transport were studied retrospectively. Mean forearm and tibial defects were 5.5 ± 0.8 and 7.6 ± 1 cm respectively, or 22.3 ± 3.6 and 20 ± 2.3% as compared with healthy segments. Most patients had numerous previous operations (2.6 ± 0.5 and 3.4 ± 0.8 per patient, respectively), extensive scars locally and post-traumatic neuropathy. There were seven infected defects. Mechanical solutions used were (1) additional osteotomy and transport of the fragment to compact the ischaemic regenerate (10 forearms, 4 tibias) and (2) compaction of the connective tissue layer in the tibial regenerate with either two 5-mm steps (two cases) or gradually (one case).
resultsBone integrity was restored in all the cases. Complete compensation of the defects was achieved in 12 patients with the first technique. Two patients with 8-cm ulna defects remained with residual discrepancy. In the forearm, mean compaction was 1.7 ± 0.4 cm. It took 25.7 ± 5.4 days followed by an average fixation period of 107.1 ± 11.8 days. In the tibia, mean longitudinal compaction by distraction measured 1.7 ± 0.8 cm. The second technique ended up with an acceptable shortening of 1 cm in two cases. Four centimeters were compressed in the third case gradually.
conclusionThe technical solutions used for mechanical effects on the ischaemic distraction regenerate resulted in its rescue and bone union in all the cases.
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