Evidence map›Paper›PMID 29934636›Full record

ArticleEye (London, England)2018

Clinical significance of ectopic inner foveal layers in patients with idiopathic epiretinal membranes.

Sibel Doguizi, Mehmet Ali Sekeroglu, Dilara Ozkoyuncu, Aslihan Esra Omay, Pelin Yilmazbas

Abstract read
In one paragraph

Article in Eye (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Evaluating ERM Stage and DRIL as predictive biomarkers for functional outcomes after iERM surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  13. Title - Long term outcomes of vitrectomy and ERM peel: Can pre-operative metamorphopsia measured using the D-Chart help improve surgical candidate selection?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Sibel DoguiziDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey. eryigits@yahoo.com.
Mehmet Ali SekerogluDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Dilara OzkoyuncuDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Aslihan Esra OmayDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Pelin YilmazbasDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo evaluate the relationship between the presence of ectopic inner foveal layers (EIFL), choroidal thickness, and visual acuity (VA) in patients with epiretinal membranes (ERM) staged by spectral-domain optical coherence tomography (SD-OCT). SUBJECTS/

methodsA total of 242 eyes of 121 patients with unilateral idiopathic ERM were prospectively evaluated. ERM stages were defined based on the SD-OCT staging system as stage 1: negligible morphological or anatomical disruption, retinal layers, and foveal pit are identified; stage 2: characteristic stretching of the outer nuclear layer, absence of foveal depression, retinal layers are identified; stage 3: continuous EIFL crossing the central foveal area, absence of foveal depression, retinal layers are identified; and stage 4: anatomical disruption of the fovea, continuous EIFL crossing the entire foveal area, retinal layers are distorted.

resultsOf 121 eyes with ERM, 23.1% had stage 1, 26.5% had stage 2, 39.7% had stage 3, and 10.7% had stage 4 disease. VA was better in eyes with stage 1 or 2 ERM than stage 3 or 4 ERM (p < 0.001). VA in logMAR was positively correlated with central foveal thickness (r = 0.557, p < 0.001) and EIFL thickness (r = 0.526, p < 0.001), but not with an outer nuclear layer thickness (r = 0.233, p = 0.123). In multivariate analysis, the presence of EIFL was an independent predictor of VA in eyes with ERM (p < 0.001). The presence and stage of ERM did not have a significant effect on choroidal thickness (p > 0.05).

conclusionsThe SD-OCT staging system according to the presence of EIFL is effective for grading retinal damage and visual loss in eyes with ERM.

Indexed as

Visual AcuityAgedChoroidCross-Sectional StudiesEpiretinal MembraneFemaleFollow-Up StudiesFovea CentralisHumansMaleProspective StudiesTomography, Optical Coherence

Identifiers

PMID29934636
PMCPMC6189081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.