Evidence map›Paper›PMID 29934491›Full record

ArticleThe Biochemical journal2018

New tools for carbohydrate sulfation analysis: heparan sulfate 2-

Dominic P Byrne, Yong Li, Krithika Ramakrishnan, Igor L Barsukov, Edwin A Yates, Claire E Eyers, Dulcé Papy-Garcia, Sandrine Chantepie, Vijayakanth Pagadala, Jian Liu and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Searching for Sulfotyrosines (sY) in a HA(pY)STACK.Journal of proteome research · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. The Emerging Roles of Heparan Sulfate 3-Frontiers in oncology · 2019
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Dominic P ByrneDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.ORCID 0000-0001-5197-345X
Yong LiDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.ORCID 0000-0002-5594-4434
Krithika RamakrishnanDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.ORCID 0000-0002-4844-0975
Igor L BarsukovDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.
Edwin A YatesDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.ORCID 0000-0001-9365-5433
Claire E EyersDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.ORCID 0000-0002-3223-5926
Dulcé Papy-GarciaLaboratory CRRET CNRS 9215, Université Paris-Est, CRRET (EA 4397/ERL CNRS 9215), UPEC, F-94010 Créteil, France.
Sandrine ChantepieLaboratory CRRET CNRS 9215, Université Paris-Est, CRRET (EA 4397/ERL CNRS 9215), UPEC, F-94010 Créteil, France.
Vijayakanth PagadalaGlycan Therapeutics, 617 Hutton Street, Raleigh, NC 27606, U.S.A.
Jian LiuUNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, U.S.A.
Carrow WellsStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, U.S.A.ORCID 0000-0003-4799-6792
David H DrewryStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, U.S.A.ORCID 0000-0001-5973-5798
William J ZuercherStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, U.S.A.ORCID 0000-0002-9836-0068
Neil G BerryDepartment of Chemistry, University of Liverpool, L69 7ZD Liverpool, U.K.ORCID 0000-0003-1928-0738
David G FernigDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K.ORCID 0000-0003-4875-4293
Patrick A EyersDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, L69 7ZB Liverpool, U.K. patrick.eyers@liverpool.ac.uk.ORCID 0000-0002-9220-2966
University of Liverpool · GBUniversity of North Carolina at Chapel Hill · USCentre National de la Recherche Scientifique · FRCotton (United States) · US

Funding

In vitro synthesis of recombinant heparan sulfateR01HL094463 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, JIAN, PAWLINSKI, RAFAL L · 2009 to 2021
$5.2M
Biotechnology and Biological Sciences Research Council BB/N021703/1NCI NIH HHS HHSN261201500019CNHLBI NIH HHS R01 HL094463Wellcome Trust 106169/ZZ14/Z
6 · The paper itself

Abstract

Sulfation of carbohydrate residues occurs on a variety of glycans destined for secretion, and this modification is essential for efficient matrix-based signal transduction. Heparan sulfate (HS) glycosaminoglycans control physiological functions ranging from blood coagulation to cell proliferation. HS biosynthesis involves membrane-bound Golgi sulfotransferases, including HS 2-

Indexed as

AnimalsAvian ProteinsChickensHeparan SulfateHumansOligosaccharidesProtein Kinase Inhibitorsraf KinasesSulfotransferasesSwineAvian ProteinsHeparan Sulfateheparan-sulfate 2-sulfotransferaseOligosaccharidesProtein Kinase Inhibitorsraf KinasesSulfotransferasesheparan sulfateheparininhibitorkinasesulfotransferase

Identifiers

PMID29934491
PMCPMC6094399
OpenAlexW2795750542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.