Evidence map›Paper›PMID 29934328›Full record

ArticleMolecular cancer research : MCR2018

BMP7 Signaling in

Hans Petter Eikesdal, Lisa M Becker, Yingqi Teng, Akane Kizu, Julienne L Carstens, Keizo Kanasaki, Hikaru Sugimoto, Valerie S LeBleu, Raghu Kalluri

Open access · greenAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hans Petter EikesdalDepartment of Cancer Biology, Metastasis Research Center, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Lisa M BeckerDepartment of Cancer Biology, Metastasis Research Center, University of Texas, MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-1879-8789
Yingqi TengDivision of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Akane KizuDivision of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Julienne L CarstensDepartment of Cancer Biology, Metastasis Research Center, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Keizo KanasakiDivision of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Hikaru SugimotoDepartment of Cancer Biology, Metastasis Research Center, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Valerie S LeBleuDepartment of Cancer Biology, Metastasis Research Center, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Raghu KalluriDepartment of Cancer Biology, Metastasis Research Center, University of Texas, MD Anderson Cancer Center, Houston, Texas. rkalluri@mdanderson.org.
Beth Israel Deaconess Medical Center · USThe University of Texas MD Anderson Cancer Center · US

Funding

Role of Fibroblasts in CancerR01CA125550 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KALLURI, RAGHU · 2008 to 2010
$1.1M
NCI NIH HHS R01 CA125550
6 · The paper itself

Abstract

Deregulated transforming growth factor-β (TGFβ) signaling is a common feature of many epithelial cancers. Deletion of

Indexed as

AnimalsBone Morphogenetic Protein 7CarcinogenesisCarcinoma, Squamous CellCell ProliferationDisease Models, AnimalEpithelial CellsGene Expression Regulation, NeoplasticHepatocyte Growth FactorHumansIntestinal MucosaReceptor, Transforming Growth Factor-beta Type IIS100 Calcium-Binding Protein A4Smad4 ProteinStomach NeoplasmsStromal Cellsbmp7 protein, mouseBone Morphogenetic Protein 7Hepatocyte Growth FactorHGF protein, mouseReceptor, Transforming Growth Factor-beta Type IIS100a4 protein, mouseS100 Calcium-Binding Protein A4Smad4 Protein

Identifiers

PMID29934328
PMCPMC6170697
OpenAlexW2809245892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.