Evidence map›Paper›PMID 29934311›Full record

ArticleThe Journal of cell biology2018

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity.

Scott R Frank, Clemens P Köllmann, Phi Luong, Giorgio G Galli, Lihua Zou, André Bernards, Gad Getz, Raffaele A Calogero, Morten Frödin, Steen H Hansen

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Mechanobiology of the Hippo-YAP Signaling Network.Cold Spring Harbor perspectives in biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Fixing the GAP: The role of RhoGAPs in cancer.European journal of cell biology · 2022
    Review
  8. Hippo Signaling in the Endometrium.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. p190RhoGAPs, theCells · 2019
    Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Scott R FrankGI Cell Biology Research Laboratory, Boston Children's Hospital and Harvard Medical School, Boston, MA.
Clemens P KöllmannGI Cell Biology Research Laboratory, Boston Children's Hospital and Harvard Medical School, Boston, MA.
Phi LuongGI Cell Biology Research Laboratory, Boston Children's Hospital and Harvard Medical School, Boston, MA.
Giorgio G GalliStem Cell Program, Boston Children's Hospital and Harvard Stem Cell Institute, Boston, MA.
Lihua ZouThe Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.ORCID 0000-0003-0686-3117
André BernardsThe Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.
Gad GetzThe Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.
Raffaele A CalogeroUniversity of Torino, Department of Molecular Biotechnology and Health Sciences, Torino, Italy.
Morten FrödinBiotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.
Steen H HansenGI Cell Biology Research Laboratory, Boston Children's Hospital and Harvard Medical School, Boston, MA steen.hansen@childrens.harvard.edu.ORCID 0000-0002-9408-4676
Boston Children's Hospital · USBroad Institute · USUniversity of Copenhagen · DKUniversity of Turin · IT

Funding

p190 RhoGAP signaling in epithelial oncogenesisR01CA205158 · NCI · BOSTON CHILDREN'S HOSPITAL · PI HANSEN, STEEN HENNING · 2017 to 2021
$2.0M
NCI NIH HHS R01 CA205158
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCell LineCell ProliferationContact InhibitionDNA-Binding ProteinsDogsEpithelial CellsGene Expression Regulation, NeoplasticGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsHippo Signaling PathwayHumansMadin Darby Canine Kidney CellsNeoplasmsNuclear ProteinsAdaptor Proteins, Signal TransducingARHGAP35 protein, humanARHGAP5 protein, humanDNA-Binding ProteinsGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsLATS1 protein, humanNuclear ProteinsPhosphoproteinsProtein Serine-Threonine KinasesRepressor Proteinsrho-Associated KinasesRNA, Small InterferingTEAD1 protein, humanTEA Domain Transcription FactorsTranscription FactorsTumor Suppressor ProteinsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID29934311
PMCPMC6122998
OpenAlexW2808880129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.