Evidence map›Paper›PMID 29934072›Full record

ArticleDiagnostic microbiology and infectious disease2018

Norovirus, astrovirus, and sapovirus among immunocompromised patients at a tertiary care research hospital.

Shelby Daniel-Wayman, Gary Fahle, Tara Palmore, Kim Y Green, D Rebecca Prevots

Open access · greenAbstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  8. Sapovirus infection as another cause of persistent viral diarrhea: case series and review of the literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2021
    Article
  16. Sapovirus: an emerging cause of childhood diarrhea.Current opinion in infectious diseases · 2020
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shelby Daniel-WaymanEpidemiology Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8 West Drive, MSC 2665, Bethesda, MD 20892, USA. Electronic address: shelby.daniel-wayman@nih.gov.
Gary FahleDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address: gfahle@cc.nih.gov.
Tara PalmoreHospital Epidemiology Service, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address: tpalmore@cc.nih.gov.
Kim Y GreenCalicivirus Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 50 Rm 6318 MSC 8026, 50 South Dr, Bethesda, MD 20892, USA. Electronic address: kim.green@nih.gov.
D Rebecca PrevotsEpidemiology Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8 West Drive, MSC 2665, Bethesda, MD 20892, USA. Electronic address: rprevots@niaid.nih.gov.
National Institutes of Health · USNational Institutes of Health Clinical Center · USNational Institute of Allergy and Infectious Diseases · US

Funding

Noroviruses and Epidemic GastroenteritisZIAAI000897 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GREEN, KIM Y. · 2009 to 2025
$29.6M
Epidemiology of Mycobacterial InfectionsZIAAI001035 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI PREVOTS, D. REBECCA · 2009 to 2025
$11.6M
The Norwalk-like Caliciviruses: Epidemic GastroenteritisZ01AI000897 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI GREEN, KIM Y. · 2001 to 2008
$3.6M
Intramural NIH HHS Z01 AI000897
6 · The paper itself

Abstract

We estimated the prevalence of astrovirus, sapovirus, and norovirus among patients enrolled in research protocols and receiving medical care at the Clinical Center of the National Institutes of Health, Bethesda, MD, a clinical research hospital with a large immunocompromised patient population. We identified patients whose fecal specimens were submitted to the Clinical Center for testing on the Biofire FilmArray Gastrointestinal Panel from September 15, 2015 through November 30, 2016. Among 442 patients with fecal specimens submitted for multiplex testing, 11% had norovirus identified, 2% had astrovirus, and 2% had sapovirus. Like norovirus, astrovirus was detected in multiple sequential samples from a single patient, consistent with chronic infection or the occurrence of multiple reinfections. Coinfection with non-viral gastrointestinal pathogens was detected in 31% of patients with positive results for norovirus, astrovirus, or sapovirus. Norovirus remains common in this immunocompromised patient population, and both sapovirus and astrovirus are present.

Indexed as

AdultAgedAged, 80 and overAstroviridae InfectionsCaliciviridae InfectionsChildChild, PreschoolCoinfectionFecesHospitalsHumansImmunocompromised HostMamastrovirusMiddle AgedNorovirusPrevalenceAstrovirusImmunocompromised hostNorovirusSapovirus

Identifiers

PMID29934072
PMCPMC11036324
OpenAlexW2806298004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.