Evidence map›Paper›PMID 29934029›Full record

ReviewTrends in cognitive sciences2018

Hippocampal Maturation Drives Memory from Generalization to Specificity.

Attila Keresztes, Chi T Ngo, Ulman Lindenberger, Markus Werkle-Bergner, Nora S Newcombe

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Neural Representations of Reward-Related Memories Shift across Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  18. Pattern separation and pattern completion in early childhood.Proceedings of the National Academy of Sciences of the United States of America · 2025
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Attila KeresztesCenter for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany. Electronic address: keresztes@mpib-berlin.mpg.de.
Chi T NgoDepartment of Psychology, Temple University, Philadelphia, PA, USA.
Ulman LindenbergerCenter for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Max Planck-University College London (UCL) Centre for Computational Psychiatry and Ageing Research, London, England, and Berlin, Germany.
Markus Werkle-BergnerCenter for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.
Nora S NewcombeDepartment of Psychology, Temple University, Philadelphia, PA, USA.

Funding

The development and neural bases of pattern separation and relational memoryF31HD090872 · NICHD · TEMPLE UNIV OF THE COMMONWEALTH · PI NGO, CHI THAO · 2017 to 2018
$60k
NICHD NIH HHS F31 HD090872
6 · The paper itself

Abstract

During early ontogeny, the rapid and cumulative acquisition of world knowledge contrasts with slower improvements in the ability to lay down detailed and long-lasting episodic memories. This emphasis on generalization at the expense of specificity persists well into middle childhood and possibly into adolescence. During this period, recognizing regularities, forming stable representations of recurring episodes, predicting the structure of future events, and building up semantic knowledge may be prioritized over remembering specific episodes. We highlight recent behavioral and neuroimaging evidence suggesting that maturational differences among subfields within the hippocampus contribute to the developmental lead-lag relation between generalization and specificity, and lay out future research directions.

Indexed as

AnimalsHippocampusHumansMemorychildhoodgeneralizationhippocampal subfieldspattern separationspecificity

Identifiers

PMID29934029
PMCPMC6086600

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.