Evidence map›Paper›PMID 29933571›Full record

ArticleInternational journal of molecular sciences2018

The Bacterial Protein CNF1 as a Potential Therapeutic Strategy against Mitochondrial Diseases: A Pilot Study.

Alessia Fabbri, Sara Travaglione, Zaira Maroccia, Marco Guidotti, Ciro Leonardo Pierri, Guido Primiano, Serenella Servidei, Stefano Loizzo, Carla Fiorentini

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects of theInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessia FabbriItalian Center for Global Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. alessia.fabbri@iss.it.
Sara TravaglioneItalian Center for Global Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. sara.travaglione@iss.it.
Zaira MarocciaItalian Center for Global Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. zaira.maroccia@iss.it.
Marco GuidottiDepartment of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. marco.guidotti@iss.it.
Ciro Leonardo PierriDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, via Orabona, 4, 70124 Bari, Italy. ciroleopierri@gmail.com.ORCID 0000-0003-1816-548X
Guido PrimianoUnità di Neurofisiopatologia, Area Neuroscienze, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168 Rome, Italy. guido.primiano@gmail.com.ORCID 0000-0001-7616-7008
Serenella ServideiUnità di Neurofisiopatologia, Area Neuroscienze, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168 Rome, Italy. Serenella.Servidei@unicatt.it.
Stefano LoizzoItalian Center for Global Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. stefano.loizzo@iss.it.
Carla FiorentiniItalian Center for Global Health, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. carla.fiorentini@iss.it.ORCID 0000-0003-1707-6282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

MutationAdenosine TriphosphateBacterial ToxinsDNA, MitochondrialElectron Transport Complex IVEscherichia coliEscherichia coli ProteinsFibroblastsGene ExpressionHumansMaleMembrane Transport ProteinsMERRF SyndromeMiddle AgedMitochondriaMitochondrial Precursor Protein Import Complex ProteinsAdenosine TriphosphateBacterial Toxinscytotoxic necrotizing factor type 1DNA, MitochondrialElectron Transport Complex IVEscherichia coli ProteinsMembrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsReceptors, Cell SurfaceTOMM20 protein, humanactin cytoskeletonadenosine triphosphatecytotoxic necrotizing factor 1mitochondrial diseasesmyoclonic epilepsy with ragged red fibers syndrome

Identifiers

PMID29933571
PMCPMC6073533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.