Evidence map›Paper›PMID 29933377›Full record

ArticlePloS one2018

Predictors and trajectories of antibiotic consumption in 22 EU countries: Findings from a time series analysis (2000-2014).

Maria Michela Gianino, Jacopo Lenzi, Marco Bonaudo, Maria Pia Fantini, Walter Ricciardi, Gianfranco Damiani

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  7. Article
  8. Article
  9. Progress towards antibiotic use targets in eight high-income countries.Bulletin of the World Health Organization · 2021
    Article
  10. Disparities in antimicrobial consumption and resistance within a country: the case of beta-lactams in Argentina.Revista panamericana de salud publica = Pan American journal of public health · 2021
    Article
  11. Article
  12. Prevalence and Determinants of Antibiotic Consumption in the Elderly during 2006-2017.International journal of environmental research and public health · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Michela GianinoDepartment of Public Health Sciences and Pediatrics, Università di Torino, Turin, Italy.
Jacopo LenziDepartment of Biomedical and Neuromotor Sciences, Alma Mater Studiorum-Università di Bologna, Italy.
Marco BonaudoDepartment of Public Health Sciences and Pediatrics, Università di Torino, Turin, Italy.ORCID 0000-0001-9278-8998
Maria Pia FantiniDepartment of Biomedical and Neuromotor Sciences, Alma Mater Studiorum-Università di Bologna, Italy.
Walter RicciardiDepartment of Public Health, Università Cattolica del Sacro Cuore, Fondazione Policlinico 'Agostino Gemelli' IRCCS, Rome, Italy.
Gianfranco DamianiDepartment of Public Health, Università Cattolica del Sacro Cuore, Fondazione Policlinico 'Agostino Gemelli' IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study analyzes the trajectories of antibiotic consumption using different indicators of patients' socioeconomic status, category and age-group of physicians.

methodsThis study uses a pooled, cross-sectional, time series analysis. The data focus on 22 European countries from 2000 to 2014 and were obtained from the European Center for Disease and Control, Organization for Economic Co-operation and Development, Eurostat and Global Economic Monitor.

resultsThere are large variations in community and hospital use of antibiotics in European countries, and the consumption of antibiotics has remained stable over the years. This applies to the community (b = 0.07, p = 0.267, 95% -0.06, 0.19, b-squared <0.01, p = 0.813, 95% = -0.01, 0.02) as well as the hospital sector (b = -0.02; p = 0.450; CI 95% = -0.06, 0.03; b-squared <0.01; p = 0.396; CI95% = > -0.01, <0.01). Some socioeconomic variables, such as level of education, income, Gini index and unemployment, are not related to the rate of antibiotic use. The age-group of physicians and general practitioners is associated with the use of antibiotics in the hospital. An increase in the proportion of young doctors (<45 years old) leads to a significant increase in antibiotics consumption, and as the percentage of generalist practitioners increases, there use of antibiotics in hospitals decreases by 0.04 DDD/1000 inhabitants.

conclusionsUnderstanding that age-groups and categories (general/specialist practitioners) of physicians may predict antibiotic consumption is potentially useful in defining more effective health care policies to reduce the inappropriate antibiotic use while promoting rational use.

Indexed as

European UnionAdultAgedAnti-Bacterial AgentsHumansMiddle AgedRegression AnalysisTime FactorsAnti-Bacterial Agents

Identifiers

PMID29933377
PMCPMC6014649

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.