Evidence map›Paper›PMID 29932847›Full record

ArticleSubstance abuse2018

A population-based examination of trends and disparities in medication treatment for opioid use disorders among Medicaid enrollees.

Bradley D Stein, Andrew W Dick, Mark Sorbero, Adam J Gordon, Rachel M Burns, Douglas L Leslie, Rosalie Liccardo Pacula

Registry-linked trialAbstract read
In one paragraph

Article in Substance abuse, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04650386 (Enhancing Office-based Buprenorphine Treatment), which is not on this map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04650386 nacompletednot on this mapstarted 2020, after this paper: background citation

Enhancing Office-based Buprenorphine Treatment: An Adaptive Psychosocial Approach

TypeinterventionalSponsorPublic Health Management CorporationRan2020 to 2024Enrolled125ConditionsOpioid-use DisorderArmsPsychosocial support determined by adaptive treatment algorithm
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Bradley D Steina RAND Corporation , Pittsburgh , Pennsylvania , USA.ORCID 0000-0003-1544-458X
Andrew W Dicka RAND Corporation , Pittsburgh , Pennsylvania , USA.
Mark Sorberoa RAND Corporation , Pittsburgh , Pennsylvania , USA.
Adam J Gordonb Department of Psychiatry , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania , USA.ORCID 0000-0002-2453-8871
Rachel M Burnsa RAND Corporation , Pittsburgh , Pennsylvania , USA.
Douglas L Leslied Departments of Internal Medicine and Psychiatry , Penn State College of Medicine , Hershey , Pennsylvania , USA.
Rosalie Liccardo Paculae RAND Corporation , Santa Monica , California , USA.
RAND Corporation · USPenn State Milton S. Hershey Medical Center · USUniversity of Pittsburgh · US

Funding

Opioid Agonist Treatment Expansion in Medicaid: The Role of BuprenorphineR01DA032881 · NIDA · RAND CORPORATION · PI STEIN, BRADLEY D · 2012 to 2014
$1.8M
NIDA NIH HHS R01 DA032881
6 · The paper itself

Abstract

backgroundMedication treatment (MT) with methadone and buprenorphine are effective treatments for opioid use disorders, but little information is available regarding the extent to which buprenorphine's approval resulted in more individuals receiving MT nor to what extent receipt of such treatment was equitable across communities.

methodsTo examine changes in MT utilization and the association between MT utilization and county-level indicators of poverty, race/ethnicity, and urbanicity, we used Medicaid claims of non-dually eligible Medicaid enrollees aged 18-64 from 14 states for 2002-2009. We generated county-level aggregate counts of MT (methadone, buprenorphine, and any MT) by year (N = 7760 county-years). We estimated count data models to identify associations between MT and county characteristics, including levels of poverty and racial/ethnic concentration.

resultsThe number of Medicaid enrollees receiving MT increased 62% from 2002 to 2009. The number of enrollees receiving methadone increased 20%, with the remaining increase resulting from buprenorphine. Urban county residents were significantly more likely to receive MT in both 2002 and 2009 than rural county residents. However, buprenorphine substantially increased MT in rural counties from 2002 to 2009. Receipt of MT increased at a much higher rate for residents of counties with lower poverty rates and lower concentrations of black and Hispanic individuals than for residents of counties without those characteristics.

conclusionsThe increase in Medicaid enrollees receiving MT in the years following buprenorphine's approval is encouraging. However, it is concerning that MT trends varied so dramatically by characteristics of the county population and that increases in utilization were substantially lower in counties with populations that historically have been disadvantaged with respect to health care access and quality. Concerted efforts are needed to ensure that MT benefits are equitably distributed across society and reach disadvantaged individuals who may be at higher risk of experiencing opioid use disorders.

Indexed as

AdolescentAdultBuprenorphineDrug UtilizationEthnicityFemaleHealthcare DisparitiesHumansMaleMedicaidMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPoverty AreasUnited StatesBuprenorphineMethadoneBuprenorphinedisparitiesMedicaidopioid use disordersubstance abuse treatment

Identifiers

PMID29932847
PMCPMC6309581
OpenAlexW2808979848

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.