ReviewChemical reviews2018
Formation and Cleavage of C-C Bonds by Enzymatic Oxidation-Reduction Reactions.
Review in Chemical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
103 citing papers in PubMed.
- Cytochrome P450 enzymes that form allenes and alkynes from prenyl groups.Nature chemical biology · 2026Article
- Biosynthetic allene and alkyne formation by enzymatic prenyl demethylation.Nature chemical biology · 2026Article
- Programmable arene ring opening unlocks the diversification of phenols.Nature chemistry · 2026Article
- Structural evolution of quinine derivatives for enhanced antifungal potency: key modifications and quantitative structure-activity relationship (QSAR) analysis.Pest management science · 2026Article
- Cephalotaxinone enzymes reveal a whole plant model for homoharringtonine biosynthesis.Nature chemical biology · 2026Article
- Microbial degradation of organophosphorus pesticides: mechanisms, environmental impacts, and future perspectives.World journal of microbiology & biotechnology · 2026Review
- Biodegradation of triclosan under non-sterile conditions by co-culture of Bacillus licheniformis and Lysinibacillus fusiformis.Bioprocess and biosystems engineering · 2026Article
- Biosynthetic allene and alkyne formation by enzymatic prenyl demethylation.bioRxiv : the preprint server for biology · 2026Article
- Mechanistic and spectroscopic characterization of human CYP17A1 in Nanodiscs.Journal of inorganic biochemistry · 2026Review
- Biocatalytic Regioselective C-Formylation of Resorcinol Derivatives.Angewandte Chemie (International ed. in English) · 2026Article
- Quantitative Treatments for Explaining the Mechanism and Kinetics of Catalytic Electron Transfers in Murburn Processes, Particularly Involving Heme Enzymes Like (Per)oxidases and P450s.BioMed research international · 2026Review
- Analysis of Chemical Composition in Three Types ofInternational journal of analytical chemistry · 2026Article
- Resistance Gene-Guided Discovery of a Fungal Spirotetramate as an Acetolactate Synthase Inhibitor.Journal of the American Chemical Society · 2025Article
- Discovery of homoharringtonine pathway enzymes reveals a whole plant model for coordinated biosynthesis.bioRxiv : the preprint server for biology · 2025Article
- Cytochrome P450The Journal of biological chemistry · 2025Article
- C-C Bond Cleavage in the Late-Stage Biosynthesis of Huperzine Alkaloids Occurs via Enzymatic Retro-Aza-Prins Reaction.Journal of the American Chemical Society · 2025Article
- Unveiling ongoing biogeochemical dynamics of CDOM from surface to deep ocean.Nature communications · 2025Article
- Immobilized Copper Complexes on Coal-Bearing Kaolin for Catalyzing Allylic Ester Synthesis via C(Molecules (Basel, Switzerland) · 2025Article
- Mechanistic Perspective on C-N and C-S Bond Construction Catalyzed by Cytochrome P450 Enzymes.ACS bio & med chem Au · 2025Review
- Mechanistic Insights into CYP199A4-Catalyzed α-Hydroxyketone Formation and Hydrogen Bond-Assisted C-C Bond Cleavage Catalyzed by the CYP199A4 F182L Mutant.International journal of molecular sciences · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Many oxidation-reduction (redox) enzymes, particularly oxygenases, have roles in reactions that make and break C-C bonds. The list includes cytochrome P450 and other heme-based monooxygenases, heme-based dioxygenases, nonheme iron mono- and dioxygenases, flavoproteins, radical S-adenosylmethionine enzymes, copper enzymes, and peroxidases. Reactions involve steroids, intermediary metabolism, secondary natural products, drugs, and industrial and agricultural chemicals. Many C-C bonds are formed via either (i) coupling of diradicals or (ii) generation of unstable products that rearrange. C-C cleavage reactions involve several themes: (i) rearrangement of unstable oxidized products produced by the enzymes, (ii) oxidation and collapse of radicals or cations via rearrangement, (iii) oxygenation to yield products that are readily hydrolyzed by other enzymes, and (iv) activation of O
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Registered trials
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