Evidence map›Paper›PMID 29932371›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2018

MicroRNAs in prostate cancer: From function to biomarker discovery.

Ahmed A Moustafa, Hogyoung Kim, Rasha S Albeltagy, Ola H El-Habit, Asim B Abdel-Mageed

Open access · bronzeAbstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  6. Review
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  13. Exposure to arsenite and cadmium induces organotoxicity and miRNAs deregulation in male rats.Environmental science and pollution research international · 2020
    Article
  14. MicroRNA-939 Directly TargetsOncoTargets and therapy · 2020
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ahmed A Moustafa1 Zoology and Entomology Department, Faculty of Science, Helwan University, Cairo 11790, Egypt.
Hogyoung Kim2 Department of Urology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Rasha S Albeltagy1 Zoology and Entomology Department, Faculty of Science, Helwan University, Cairo 11790, Egypt.
Ola H El-Habit1 Zoology and Entomology Department, Faculty of Science, Helwan University, Cairo 11790, Egypt.
Asim B Abdel-Mageed2 Department of Urology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Helwan University · EGTulane University · US

Funding

Targeting Tumor-Derived exRNA-Containing Microvesicles by High Throughput ScreeniUH2TR000928 · NCATS · TULANE UNIVERSITY OF LOUISIANA · PI ABDEL-MAGEED, ASIM B · 2013 to 2015
$1.3M
NCATS NIH HHS UH2 TR000928
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a small functional non-coding RNAs that post-transcriptionally regulate gene expression through mRNA degradation or translational repression. miRNAs are key regulatory components of various cellular networks. Current evidence support that multiple mammalian genome-encoded miRNAs impact the cellular biology, including proliferation, apoptosis, differentiation, and tumorigenesis, by targeting specific subsets of mRNAs. This minireview is focused on the current themes underlying the interactions between miRNAs and their mRNA targets and pathways in prostate tumorigenesis and progression, and their potential clinical utility as biomarkers for prostate cancer. Impact statement The primary goal of this article was to review recent literature on miRNA biogenesis and further elaborate on the identity of newly discovered miRNAs and their potential functional significance in the complex biological network associated with prostate tumorigenesis and disease progression and as biomarkers for prostate cancer.

Indexed as

Biomarkers, TumorHumansMaleMicroRNAsProstatic NeoplasmsBiomarkers, TumorMicroRNAsbiomarkersmicroRNAonco-miRProstate cancertumor suppressor miRNAs

Identifiers

PMID29932371
PMCPMC6022910
OpenAlexW2808904652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.