Evidence map›Paper›PMID 29932161›Full record

ReviewSensors (Basel, Switzerland)2018

Recent Advances in Enhancement Strategies for Electrochemical ELISA-Based Immunoassays for Cancer Biomarker Detection.

Sunil K Arya, Pedro Estrela

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Review
  3. Review: Detection of Cancer Biomarkers from a Clinical Perspective.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Surface Engineering of MXene and Functional Fullerenols for Cancer Biomarker 'eIFLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  9. Article
  10. Review
  11. A compact microfluidic laser-induced fluorescence immunoassay system using avalanche photodiode for rapid detection of alpha-fetoprotein.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
  12. Review
  13. Article
  14. A Spectrofluorometric Method for Real-Time Graft Assessment and Patient Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  15. Review
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sunil K AryaCentre for Biosensors, Bioelectronics and Biodevices (C3Bio) and Department of Electronic & Electrical Engineering, University of Bath, Claverton Down, Bath BA2 7AY, UK. sunilarya333@gmail.com.
Pedro EstrelaCentre for Biosensors, Bioelectronics and Biodevices (C3Bio) and Department of Electronic & Electrical Engineering, University of Bath, Claverton Down, Bath BA2 7AY, UK. P.Estrela@bath.ac.uk.ORCID 0000-0001-6956-1146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrochemical enzyme-linked immunosorbent assay (ELISA)-based immunoassays for cancer biomarker detection have recently attracted much interest owing to their higher sensitivity, amplification of signal, ease of handling, potential for automation and combination with miniaturized analytical systems, low cost and comparative simplicity for mass production. Their developments have considerably improved the sensitivity required for detection of low concentrations of cancer biomarkers present in bodily fluids in the early stages of the disease. Recently, various attempts have been made in their development and several methods and processes have been described for their development, amplification strategies and testing. The present review mainly focuses on the development of ELISA-based electrochemical immunosensors that may be utilized for cancer diagnosis, prognosis and therapy monitoring. Various fabrication methods and signal enhancement strategies utilized during the last few years for the development of ELISA-based electrochemical immunosensors are described.

Indexed as

Electrochemical TechniquesBiomarkers, TumorEnzyme-Linked Immunosorbent AssayHumansNeoplasmsOxidation-ReductionBiomarkers, Tumorantibodiescancer detectionelectrochemical ELISAimmunoassayserum

Identifiers

PMID29932161
PMCPMC6069457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.