Evidence map›Paper›PMID 29932041›Full record

ArticleEpidemiology and infection2018

Staphylococcus aureus in the nose and throat of Iowan families.

B M Hanson, A E Kates, S M O'Malley, E Mills, L A Herwaldt, J C Torner, J D Dawson, S A Farina, C Klostermann, J Y Wu and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Antibiotics (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Determinants of maturation of theJournal of bacteriology · 2024
    Article
  5. Frontiers in microbiomes · 2024
    Article
  6. Article
  7. Evaluation ofPathogens (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Infection and drug resistance · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

B M HansonUniversity of Iowa,Iowa City,Iowa,USA.
A E KatesUniversity of Iowa,Iowa City,Iowa,USA.
S M O'MalleyUniversity of Iowa,Iowa City,Iowa,USA.
E MillsUniversity of Iowa,Iowa City,Iowa,USA.
L A HerwaldtUniversity of Iowa,Iowa City,Iowa,USA.
J C TornerUniversity of Iowa,Iowa City,Iowa,USA.
J D DawsonUniversity of Iowa,Iowa City,Iowa,USA.
S A FarinaUniversity of Iowa,Iowa City,Iowa,USA.
C KlostermannUniversity of Iowa,Iowa City,Iowa,USA.
J Y WuUniversity of Iowa,Iowa City,Iowa,USA.
M K QuickUniversity of Iowa,Iowa City,Iowa,USA.
B M ForsheyUniversity of Iowa,Iowa City,Iowa,USA.
T C SmithKent State University,Kent,Ohio,USA.ORCID 0000-0003-3747-1116
University of Iowa · USKent State University · US

Funding

NIAID NIH HHS L30 AI084653
6 · The paper itself

Abstract

The study objective was to determine the prevalence of Staphylococcus aureus colonisation in the nares and oropharynx of healthy persons and identify any risk factors associated with such S. aureus colonisation. In total 263 participants (177 adults and 86 minors) comprising 95 families were enrolled in a year-long prospective cohort study from one urban and one rural county in eastern Iowa, USA, through local newspaper advertisements and email lists and through the Keokuk Rural Health Study. Potential risk factors including demographic factors, medical history, farming and healthcare exposure were assessed. Among the participants, 25.4% of adults and 36.1% minors carried S. aureus in their nares and 37.9% of adults carried it in their oropharynx. The overall prevalence was 44.1% among adults and 36.1% for minors. Having at least one positive environmental site for S. aureus in the family home was associated with colonisation (prevalence ratio: 1.34, 95% CI: 1.07-1.66). The sensitivity of the oropharyngeal cultures was greater than that of the nares cultures (86.1% compared with 58.2%, respectively). In conclusion, the nares and oropharynx are both important colonisation sites for healthy community members and the presence of S. aureus in the home environment is associated with an increased probability of colonisation.

Indexed as

AdolescentAdultAgedCarrier StateChildChild, PreschoolFemaleHumansInfantIowaMaleMiddle AgedNoseOropharynxPrevalenceProspective StudiesCommunityepidemiologyMRSAS. aureus

Identifiers

PMID29932041
PMCPMC6135667
OpenAlexW2808892290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.