Evidence map›Paper›PMID 29931657›Full record

Trial reportEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018

Vitamin D supplementation to persistent carriers of MRSA-a randomized and placebo-controlled clinical trial.

Linda Björkhem-Bergman, Catharina Missailidis, John Karlsson-Valik, Ann Tammelin, Lena Ekström, Matteo Bottai, Ulf Hammar, Gudrun Lindh, Peter Bergman

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Frontiers in cellular and infection microbiology · 2022
    Review
  5. Article
  6. Article
  7. Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Linda Björkhem-BergmanDivision of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society (NVS), KI Huddinge, Stockholm, Sweden.
Catharina MissailidisDepartment of Laboratory Medicine (LABMED), Clinical Microbiology, KI Huddinge, Stockholm, Sweden.
John Karlsson-ValikDivision of Infectious Diseases, Department of Medicine Solna (MedS), KI, Stockholm, Sweden.
Ann TammelinDivision of Infectious Diseases, Department of Medicine Solna (MedS), KI, Stockholm, Sweden.
Lena EkströmDepartment of Laboratory Medicine (LABMED), Clinical Pharmacology, KI Huddinge, Stockholm, Sweden.
Matteo BottaiBiostatistics Unit, Institute of Environmental Medicine (IMM), KI, Stockholm, Sweden.
Ulf HammarBiostatistics Unit, Institute of Environmental Medicine (IMM), KI, Stockholm, Sweden.
Gudrun LindhDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Peter BergmanDepartment of Laboratory Medicine (LABMED), Clinical Microbiology, KI Huddinge, Stockholm, Sweden. peter.bergman@ki.se.ORCID http://orcid.org/0000-0003-3306-3713
Karolinska University Hospital · SEMarine Environmental Analysis (Sweden) · SEStockholm South General Hospital · SE

Funding

Stockholms Läns Landsting 2013-0317Vetenskapsrådet 2013-1047
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to all beta-lactam antibiotics and can cause severe infections that are difficult to treat. Eradication strategies with conventional antibiotics are not always effective and alternative approaches are warranted. Here, we tested the hypothesis that daily supplementation with vitamin D for 12 months would reduce MRSA carriage rates among a group of persistent carriers. This was a double-blind, placebo-controlled randomized trial with n = 65 persistent MRSA carriers with 25-hydroxy vitamin D

Indexed as

Dietary SupplementsAdultCarrier StateDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedPlacebosStaphylococcal InfectionsSwedenVitamin DPlacebosVitamin DClinical trialImmunityMethicillin-resistant S. aureus (MRSA)Vitamin D

Identifiers

PMID29931657
PMCPMC6133039
OpenAlexW2809516958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.