ArticleBreast cancer research and treatment2018
Validation of the new AJCC eighth edition of the TNM classification for breast cancer with a single-center breast cancer cohort.
Article in Breast cancer research and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 33 citations in OpenAlex.
- Validation of the AJCC prognostic stage for HER2-positive breast cancer in the ShortHER trial.BMC medicine · 2019Trial
- The American Joint Committee on Cancer (AJCC) Breast Cancer Staging, Eighth Edition, is more Reflective of Cancer Biology than the Seventh Edition.Annals of surgical oncology · 2025Article
- Validation of the AJCC 8th Edition Breast Cancer Prognostic Staging System in Legacy Alliance Trials (AFT-01).Annals of surgical oncology · 2024Article
- Impact of the COVID-19 pandemic on breast cancer pathological stage at diagnosis in Tunisian patients.Breast disease · 2024Article
- Clinicopathological Factors Affecting Breast Cancer Survival in Jamaican Women: A Retrospective Review.Journal of racial and ethnic health disparities · 2023Article
- A Novel lncRNA Panel for Risk Stratification and Immune Landscape in Breast Cancer Patients.International journal of general medicine · 2022Article
- The Will Rogers phenomenon, breast cancer and race.BMC cancer · 2021Article
- A Systemic Inflammation Response Score for Prognostic Prediction of Breast Cancer Patients Undergoing Surgery.Journal of personalized medicine · 2021Article
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- Deep Learning-Based Prediction Model for Breast Cancer Recurrence Using Adjuvant Breast Cancer Cohort in Tertiary Cancer Center Registry.Frontiers in oncology · 2021Article
- The comparison of the anatomic stage and pathological prognostic stage according to the AJCC 8th edition for the prognosis in Japanese breast cancer patients: data from a single institution.Breast cancer (Tokyo, Japan) · 2020Observational
- Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer.Scientific reports · 2020Article
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- Personalized medicine in breast cancer: a step forward.Annals of translational medicine · 2019Article
- Anatomy is not enough: the crucial role of biology and genetics in AJCC eighth edition of the TNM classification for breast cancer.Annals of translational medicine · 2019Article
- Validation of the pathological prognostic staging system proposed in the revised eighth edition of the AJCC staging manual in different molecular subtypes of breast cancer.Virchows Archiv : an international journal of pathology · 2019Article
- Identification of a 4-mRNA metastasis-related prognostic signature for patients with breast cancer.Journal of cellular and molecular medicine · 2019Article
- Clinical and molecular prognostic markers of survival after surgery for gastric cancer: tumor-node-metastasis staging system and beyond.Translational gastroenterology and hepatology · 2019Review
- Socioeconomic Impact of OncotypeDX on Breast Cancer Treatment: Preliminary Results.In vivo (Athens, Greece)Article
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13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe new eighth edition TNM classification by the AJCC for breast cancer (BC) incorporates biologic factors and gene expression prognostic panels, in addition to traditional anatomic factors. In this study, we evaluated the prognostic value of this new staging system compared to the previous AJCC 7th edition staging system.
methodsWe conducted a retrospective analysis of women with stage I, II, or III BC who underwent curative surgery with/without adjuvant systemic therapy at Samsung Medical Center between July 2004 and December 2008.
resultsOf 3,208 BCs, this study was analyzed using the information of 2,790 BC patients. Hormone receptor-positive (HR+) and human epidermal growth factor 2 (HER2)- BCs were observed in 62.9% of BCs, HR+/ HER2+ in 9.3%, HR-/HER2- in 17.0%, and HR-/HER2+ in 10.8%. In survival analysis, we observed 245 distant recurrences and 198 deaths caused by BC progression. The median follow-up duration was 116.2 months. 10-year disease-specific survival (DSS) rates according to the AJCC 7th edition criteria were 97.2% of stage IA, 100% of IB, 94.9% of IIA, 87.9% of IIB, 86.4% of IIIA, 95.7% of IIIB, and 65.7% of IIIC (p < 0.001). After applying 8th edition criteria, the 10-year DSS rates were 98.1% of stage IA, 97.7% of IB, 93.8% of IIA, 92.7% of IIB, 88.2% of IIIA, 80.8% of IIIB, and 70.3% of IIIC (p < 0.001).
conclusionsThe AJCC 8th edition clinical staging system provides a good prognostic value and addresses the weakness of the AJCC 7th edition, which uses only anatomical pathologic staging.
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