ArticleCellular and molecular gastroenterology and hepatology2018
Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells.
Abstract read
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Article in Cellular and molecular gastroenterology and hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Extracellular Vesicles and Plant-Derived Vesicles in Cancer: From Mechanisms to Clinical Translation.Pharmaceutics · 2026Review
- Small extracellular vesicles in tumor metabolism and immune escape: biomarkers and therapeutic opportunities.Molecular biology reports · 2026Review
- Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties.Nature cell biology · 2025Article
- Obese Adipose Tissue Extracellular Vesicles Activate Mitochondrial Fatty Acid β-oxidation to Drive Colonic Stemness.Cellular and molecular gastroenterology and hepatology · 2025Article
- Cancer EV stimulate endothelial glycolysis to fuel protein synthesis via mTOR and AMPKα activation.Journal of extracellular vesicles · 2024Article
- Emerging Roles of Small Extracellular Vesicles in Gastrointestinal Cancer Research and Therapy.Cancers · 2024Review
- Regulatory role of exosomes in colorectal cancer progression and potential as biomarkers.Cancer biology & medicine · 2023Review
- Context-specific regulation of extracellular vesicle biogenesis and cargo selection.Nature reviews. Molecular cell biology · 2023Review
- Horizontal Transfer of Malignant Traits and the Involvement of Extracellular Vesicles in Metastasis.Cells · 2023Review
- Small extracellular vesicle-mediated metabolic reprogramming: from tumors to pre-metastatic niche formation.Cell communication and signaling : CCS · 2023Review
- Recent advances microRNAs and metabolic reprogramming in colorectal cancer research.Frontiers in oncology · 2023Review
- Recent Advances in the Study of Extracellular Vesicles in Colorectal Cancer.Gastroenterology · 2022Review
- Extracellular vesicles and particles impact the systemic landscape of cancer.The EMBO journal · 2022Review
- Identification of stromal microenvironment characteristics and key molecular mining in pancreatic cancer.Discover oncology · 2022Article
- Sunitinib and Axitinib increase secretion and glycolytic activity of small extracellular vesicles in renal cell carcinoma.Cancer gene therapy · 2022Article
- The Role of Extracellular Vesicles in Metabolic Reprogramming of the Tumor Microenvironment.Cells · 2022Review
- Roles of Exosome Genomic DNA in Colorectal Cancer.Frontiers in pharmacology · 2022Review
- Liquid biopsy approaches and immunotherapy in colorectal cancer for precision medicine: Are we there yet?Frontiers in oncology · 2022Review
- Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.Nature cell biology · 2021Article
- Emerging role of tumor-derived extracellular vesicles in T cell suppression and dysfunction in the tumor microenvironment.Journal for immunotherapy of cancer · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Qin ZhangDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Dennis K JeppesenDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
James N HigginbothamDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Michelle Demory BecklerDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Emily J PoulinDepartment of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee.
Alex J WalshDepartment of Biomedical Engineering, Vanderbilt University Medical Center, Nashville, Tennessee.
Melissa C SkalaDepartment of Biomedical Engineering, Vanderbilt University Medical Center, Nashville, Tennessee.
Eliot T McKinleyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
H Charles ManningDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Matthew R HightVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee.
Michael L SchulteDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Kimberly R WattDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
G Daniel AyersBiostatistics Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Melissa M WolfDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
Gabriela AndrejevaDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
Jeffrey C RathmellDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
Jeffrey L FranklinDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Robert J CoffeyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MUnderstanding and Controlling p120 Dysfunction in CRCP50CA095103 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COFFEY, ROBERT J. · 2002 to 2017
$33.6MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MIntegrated approach to study early and late events in colonic neoplasia: mouse to manR35CA197570 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2017 to 2026
$9.4MMultidisciplinary Training in Basic and Translational Imaging of CancerR25CA092043 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MANNING, HENRY CHARLES · 2001 to 2015
$6.6MTrafficking of eRNAs in K-Ras Mutant Colon CancerU19CA179514 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COFFEY, ROBERT J. · 2013 to 2017
$5.3MRole of EGFR ligand-containing exosomes in colorectal cancerR01CA163563 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COFFEY, ROBERT J. · 2013 to 2016
$1.7MRadiochemistry Equipment for Molecular Imaging Tracer ProductionS10OD023543 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MANNING, HENRY CHARLES · 2017 to 2017
$359kRadiofluorination Equipment for PET Imaging ResearchS10OD019963 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MANNING, HENRY CHARLES · 2016 to 2016
$291kNCI NIH HHS P30 CA068485NCI NIH HHS P50 CA095103NCI NIH HHS R01 CA163563NCI NIH HHS R25 CA092043NCI NIH HHS R35 CA197570NCI NIH HHS U19 CA179514NIDDK NIH HHS P30 DK058404NIH HHS S10 OD019963NIH HHS S10 OD023543
Abstract
PubMed holds no abstract for this paper.
Indexed as
18F-FSPG, (S)-4-(3-[18F]-fluoropropyl)-L-glutamic acidApc, adenomatous polyposis coliCRC, colorectal cancerDLD-1, Daniel L. Dexter derived 1FAD, flavin adenine dinucleotideGLUT-1, glucose transporter 1KO, knockoutKRAS, Kirsten rat sarcoma viral oncogene homologNADH, Nicotinamide adenine dinucleotide reducedWT, wild-type
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.