ReviewFrontiers in plant science2018
Glutathione S-Transferases: Role in Combating Abiotic Stresses Including Arsenic Detoxification in Plants.
Review in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
166 citing papers in PubMed, 1 synthesis or guideline pooled it, 439 citations in OpenAlex.
- Toxic Effects of Glyphosate on the Nervous System: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Integrative genomics resolves rice loci associated with acidic soil-related aluminum, cadmium, and manganese stress responses.Plant cell reports · 2026Article
- TheInternational journal of molecular sciences · 2026Article
- Integrative Physiological-Biochemical and Multi-Omics Analyses Reveal Regulatory Mechanisms Governing Growth, Selenium Accumulation, and Nutrient Metabolism in Selenium Biologically Enhanced Quinoa (Chenopodium quinoa Willd.).Journal of agricultural and food chemistry · 2026Article
- The Circadian Oscillator Affects Both Glutathione Homeostasis and Its Response to Salt Stress in Arabidopsis thaliana.Plant, cell & environment · 2026Article
- Article
- Impact of Bisphenol A on root development, oxidative stress, and arbuscular mycorrhizal symbiosis in transformed root of Daucus carota L.BMC ecology and evolution · 2026Article
- Integrated physiological and transcriptomic analyses reveal MT-mediated aluminum tolerance mechanisms in celery.BMC plant biology · 2026Article
- Phytohormonal and Transcriptomic Mechanisms of Multigenerational Stress Memory in Wheat Under Weed Competition.Plant, cell & environment · 2026Article
- Evolutionary diversity of cell-type-specific expression and stress response in Brassicaceae roots.Nature communications · 2026Article
- Pan-Genome-Wide Analysis and Expression Profiling of the Potato GST Gene Family.Plants (Basel, Switzerland) · 2026Article
- Evolutionary diversity of cell-type-specific expression and stress response in Brassicaceae roots.bioRxiv : the preprint server for biology · 2026Article
- Genome-wide identification and light-quality-dependent characterization of Glutathione S-transferase genes involved in anthocyanin accumulation in Rhododendron.BMC plant biology · 2026Article
- Cell-Type-Specific and Variety-Specific Responses to Salt Stress in Wheat Root Revealed by Single-Cell Transcriptomics.Plant biotechnology journal · 2026Article
- The non-catalytic binding of auxin, cytokinin and salicylic acid by tomato Phi class glutathione transferases: insights from computational modelling.Plant molecular biology · 2026Article
- The RNA mPlant biotechnology journal · 2026Article
- Molecular identification, isolation and functional characterization of a glutathione S-transferase gene CsGST in saffron (Crocus sativus L.).Scientific reports · 2026Article
- Heavy metal transformation in mangrove ecosystems: a multi-scale perspective from intertidal dynamics to plant adaptive responses.Forestry research · 2026Review
- Integrated transcriptomic and physiological analysis reveals cadmium stress responses in kiwifruit rootstockFrontiers in plant science · 2026Article
- Low dose ionising radiation elicits MPTP comparable alterations in locomotor Function, oxidative balance and mitochondrial homeostasis in zebrafish embryos.Scientific reports · 2025Article
106 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arsenic (As), naturally occurring metalloid and a potential hazardous material, is found in low concentrations in the environment and emerges from natural sources and anthropogenic activities. The presence of As in ground water, which is used for irrigation, is a matter of great concern since it affects crop productivity and contaminates food chain. In plants, As alters various metabolic pathways in cells including the interaction of substrates/enzymes with the sulfhydryl groups of proteins and the replacement of phosphate in ATP for energy. In addition, As stimulates the generation of free radicals and reactive oxygen species (ROS), resulting in oxidative stress. Glutathione S-transferases (GSTs) quench reactive molecules with the addition of glutathione (GSH) and protect the cell from oxidative damage. GSTs are a multigene family of isozymes, known to catalyze the conjugation of GSH to miscellany of electrophilic and hydrophobic substrates. GSTs have been reported to be associated with plant developmental processes and are responsive to multitude of stressors. In past, several studies suggested involvement of plant GST gene family in As response due to the requirement of sulfur and GSH in the detoxification of this toxic metalloid. This review provides updated information about the role of GSTs in abiotic and biotic stresses with an emphasis on As uptake, metabolism, and detoxification in plants. Further, the genetic manipulations that helped in enhancing the understanding of the function of GSTs in abiotic stress response and heavy metal detoxification has been reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.