Evidence map›Paper›PMID 29930257›Full record

Trial reportScientific reports2018

Deep-learned 3D black-blood imaging using automatic labelling technique and 3D convolutional neural networks for detecting metastatic brain tumors.

Yohan Jun, Taejoon Eo, Taeseong Kim, Hyungseob Shin, Dosik Hwang, So Hi Bae, Yae Won Park, Ho-Joon Lee, Byoung Wook Choi, Sung Soo Ahn

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yohan JunSchool of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea.
Taejoon EoSchool of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea.
Taeseong KimSchool of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea.
Hyungseob ShinSchool of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea.
Dosik HwangSchool of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea. dosik.hwang@yonsei.ac.kr.ORCID 0000-0002-2217-2837
So Hi BaeDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science and Center for Clinical Image Data Science, Yonsei University College of Medicine, Seoul, Korea.
Yae Won ParkDepartment of Radiology, Ewha Womans University College of Medicine, Seoul, Korea.
Ho-Joon LeeDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science and Center for Clinical Image Data Science, Yonsei University College of Medicine, Seoul, Korea.
Byoung Wook ChoiDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science and Center for Clinical Image Data Science, Yonsei University College of Medicine, Seoul, Korea.
Sung Soo AhnDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science and Center for Clinical Image Data Science, Yonsei University College of Medicine, Seoul, Korea. sungsoo@yuhs.ac.ORCID 0000-0002-0503-5558

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Black-blood (BB) imaging is used to complement contrast-enhanced 3D gradient-echo (CE 3D-GRE) imaging for detecting brain metastases, requiring additional scan time. In this study, we proposed deep-learned 3D BB imaging with an auto-labelling technique and 3D convolutional neural networks for brain metastases detection without additional BB scan. Patients were randomly selected for training (29 sets) and testing (36 sets). Two neuroradiologists independently evaluated deep-learned and original BB images, assessing the degree of blood vessel suppression and lesion conspicuity. Vessel signals were effectively suppressed in all patients. The figure of merits, which indicate the diagnostic performance of radiologists, were 0.9708 with deep-learned BB and 0.9437 with original BB imaging, suggesting that the deep-learned BB imaging is highly comparable to the original BB imaging (difference was not significant; p = 0.2142). In per patient analysis, sensitivities were 100% for both deep-learned and original BB imaging; however, the original BB imaging indicated false positive results for two patients. In per lesion analysis, sensitivities were 90.3% for deep-learned and 100% for original BB images. There were eight false positive lesions on the original BB imaging but only one on the deep-learned BB imaging. Deep-learned 3D BB imaging can be effective for brain metastases detection.

Indexed as

Deep LearningAgedBlood VesselsBrain NeoplasmsFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedSensitivity and Specificity

Identifiers

PMID29930257
PMCPMC6013490

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.