Evidence map›Paper›PMID 29930245›Full record

ArticleScientific reports2018

Nationwide survey on the organ-specific prevalence and its interaction with sarcoidosis in Japan.

Takeshi Hattori, Satoshi Konno, Noriharu Shijubo, Tetsuo Yamaguchi, Yukihiko Sugiyama, Sakae Honma, Naohiko Inase, Yoichi M Ito, Masaharu Nishimura

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Use of fatigue assessment scale and small fiber neuropathy screening list in Japanese patients with sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Autoantibodies in sarcoidosis: Innocent bystander or promising biomarker for organ involvement?Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  12. Review
  13. Article
  14. Sarcoidosis-Related Uveitis: A Review.Journal of clinical medicine · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takeshi HattoriFirst Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan.
Satoshi KonnoFirst Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan. satkonno@med.hokudai.ac.jp.
Noriharu ShijuboDepartment of Respiratory Medicine, JR Sapporo Hospital, Sapporo, Japan.
Tetsuo YamaguchiShinjuku-Kaijo Bldg. Clinic, Tokyo, Japan.
Yukihiko SugiyamaDepartment of Pulmonary Medicine, Nerima Hikarigaoka Hospital, Tokyo, Japan.
Sakae HonmaDivision of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, Japan.
Naohiko InaseDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Yoichi M ItoDepartment of Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Japan.ORCID 0000-0001-5073-0827
Masaharu NishimuraFirst Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies attempted to characterize the subjects with sarcoidosis according to differences in sex, age, and the presence of specific organ involvement. However, significant interactions among these factors precluded a clear conclusion based on simple comparison. This study aimed to clarify the age- and sex-stratified prevalence of specific organ involvement and the heterogenous nature of sarcoidosis. Using the data of 9,965 patients who were newly registered into a database at the Ministry of Health, Labour and Welfare, Japan between 2002 and 2011, we evaluated the age- and sex-specific prevalence of the eye, lung, and skin involvement of sarcoidosis. We also attempted corresponding analysis considering multiple factors. As compared with several decades ago, the monophasic age distribution in men became biphasic, and the biphasic distribution in women, monophasic. The prevalence of pulmonary and cutaneous lesions was significantly associated with age, whereas the prevalence of ocular involvement showed a biphasic pattern. The prevalence of bilateral hilar lymphadenopathy was significantly higher, whereas the prevalence of diffuse lung shadow was significantly lower, in subjects with ocular involvement than those without ocular involvement. Corresponding analysis visually clarified the complex interactions among factors. Our results contribute to a better understanding of the heterogeneous features of sarcoidosis.

Indexed as

AdultAgedEyeFemaleHumansJapanLungMaleMiddle AgedPrevalenceSarcoidosisSkinSurveys and Questionnaires

Identifiers

PMID29930245
PMCPMC6013472

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.