ArticleThe Journal of experimental medicine2018
A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival.
Open access · bronzeAbstract read
In one paragraph
Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 60 citations in OpenAlex.
- Commensals join the effector game.Nature immunology · 2026Article
- Type I and III interferons synergize with TNF to promote virally-triggered damage to the intestinal epithelium.bioRxiv : the preprint server for biology · 2026Article
- Monogenic forms of inflammatory bowel disease: Genetic mechanisms, models, and clinical implications.Molecular medicine (Cambridge, Mass.) · 2026Review
- TNIP1 Impacts Prognosis by Modulating the Immune Microenvironment in BRCA.Biochemical genetics · 2026Article
- The cGAS-STING pathway in pulmonary infectious and sterile inflammation: differences, connections, and therapeutic implications.Frontiers in immunology · 2026Review
- Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Conformational Analyses of the AHD1-UBAN Region of TNIP1 Highlight Key Amino Acids for Interaction with Ubiquitin.Biomolecules · 2025Article
- Critical Analysis of Cytoplasmic Progression of Inflammatory Signaling Suggests Potential Pharmacologic Targets for Wound Healing and Fibrotic Disorders.Biomedicines · 2024Review
- Targeting necroptosis: a promising avenue for respiratory disease treatment.Cell communication and signaling : CCS · 2024Review
- The Complexity of Being A20: From Biological Functions to Genetic Associations.Journal of clinical immunology · 2024Review
- Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis.The Journal of clinical investigation · 2023Article
- Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling.International journal of molecular sciences · 2023Review
- Death by TNF: a road to inflammation.Nature reviews. Immunology · 2023Review
- TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.The Journal of cell biology · 2023Article
- A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1): a novel modulator of mitochondrial autophagy.American journal of physiology. Cell physiology · 2023Article
- A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer.Gastro hep advances · 2023Article
- Breaking bad: necroptosis in the pathogenesis of gastrointestinal diseases.Frontiers in immunology · 2023Review
- Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development.Cell death and differentiation · 2022Article
- Article
- Intestinal inflammation alters the antigen-specific immune response to a skin commensal.Cell reports · 2022Article
Corrections and comments
- Commented on by
Authors and funding
13 authors at 1 institution in 1 country.
Michael G KattahDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Ling ShaoDepartment of Medicine, University of California, San Francisco, San Francisco, CA.ORCID 0000-0002-0285-9287
Yenny Y RosliDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Hiromichi ShimizuDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Michael I WhangDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Rommel AdvinculaDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Philip AchacosoDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Sanjana ShahDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Bao H DuongDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Michio OnizawaDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Priscilia TanbunDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Barbara A MalynnDepartment of Medicine, University of California, San Francisco, San Francisco, CA.ORCID 0000-0001-6986-1261
Averil MaDepartment of Medicine, University of California, San Francisco, San Francisco, CA averil.ma@ucsf.edu.ORCID 0000-0003-4817-1258
University of California, San Francisco · US
Funding
TRAINING PROGRAM IN DISGESTIVE DISEASES AND NUTRITIONT32DK007007 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AVERIL I MA · 1986 to 2026
$6.4MA20 Mediated Regulation of Colitis and SpondyloarthritisR01DK095693 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MA, AVERIL I · 2012 to 2021
$3.1MThe Ubiquitin Editing Enzyme A20 Preserves Intestinal Epithelial Cell HomeostasisK08DK100462 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHAO, LING · 2014 to 2018
$805kNIDDK NIH HHS K08 DK100462NIDDK NIH HHS R01 DK095693NIDDK NIH HHS T32 DK007007
Abstract
A20 (
Indexed as
Adaptor Proteins, Signal TransducingAnimalsApoptosisCaspasesCell SurvivalEnterocolitisEpithelial CellsGene DeletionIntestinesMiceOrganoidsReceptor-Interacting Protein Serine-Threonine KinasesSignal TransductionTumor Necrosis Factor-alphaTumor Necrosis Factor alpha-Induced Protein 3Adaptor Proteins, Signal TransducingCaspasesReceptor-Interacting Protein Serine-Threonine KinasesRipk1 protein, mouseRipk3 protein, mouseTnfaip3 protein, mouseTnip2 protein, mouseTumor Necrosis Factor-alphaTumor Necrosis Factor alpha-Induced Protein 3
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.