Evidence map›Paper›PMID 29930085›Full record

ArticleJournal of cell science2018

Local and global Cdc42 guanine nucleotide exchange factors for fission yeast cell polarity are coordinated by microtubules and the Tea1-Tea4-Pom1 axis.

Ye Dee Tay, Marcin Leda, Andrew B Goryachev, Kenneth E Sawin

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ye Dee TayWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK.ORCID 0000-0002-7031-7789
Marcin LedaSynthSys - Centre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, CH Waddington Building, Max Born Crescent, Edinburgh EH9 3BF, UK.ORCID 0000-0001-8422-9459
Andrew B GoryachevSynthSys - Centre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, CH Waddington Building, Max Born Crescent, Edinburgh EH9 3BF, UK andrew.goryachev@ed.ac.uk ken.sawin@ed.ac.uk.ORCID 0000-0002-1332-4819
Kenneth E SawinWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK andrew.goryachev@ed.ac.uk ken.sawin@ed.ac.uk.ORCID 0000-0002-2607-2219
University of Edinburgh · GBWellcome Centre for Cell Biology · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K021699/1Wellcome Trust 094517
6 · The paper itself

Abstract

The conserved Rho-family GTPase Cdc42 plays a central role in eukaryotic cell polarity. The rod-shaped fission yeast

Indexed as

cdc42 GTP-Binding ProteinCell PolarityGuanine Nucleotide Exchange FactorsMicrotubule-Associated ProteinsMicrotubulesProtein KinasesRho Guanine Nucleotide Exchange FactorsSchizosaccharomycesSchizosaccharomyces pombe Proteinscdc42 GTP-Binding ProteinGef1 protein, S pombeGuanine Nucleotide Exchange FactorsMicrotubule-Associated ProteinsPom1 protein, S pombeProtein KinasesRho Guanine Nucleotide Exchange Factorsscd1 protein, S pombeSchizosaccharomyces pombe ProteinsTea1 protein, S pombeTea4 protein, S pombeCdc42Cell polarityFission yeastGuanine nucleotide exchange factorMicrotubules

Identifiers

PMID29930085
PMCPMC6080602
OpenAlexW2766796127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.