Evidence map›Paper›PMID 29930006›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2018

Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis.

Theodora A M Claushuis, Sacha F de Stoppelaar, Alex F de Vos, Anita E Grootemaat, Nicole N van der Wel, Joris J T H Roelofs, Jerry Ware, Cornelis Van't Veer, Tom van der Poll

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  8. Annual Report on Sex in Preclinical Studies:Arteriosclerosis, thrombosis, and vascular biology · 2020
    Review
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Theodora A M ClaushuisFrom the Center for Experimental and Molecular Medicine (T.A.M.C., S.F.d.S., A.F.d.V., C.v.V., T.v.d.P.).
Sacha F de StoppelaarFrom the Center for Experimental and Molecular Medicine (T.A.M.C., S.F.d.S., A.F.d.V., C.v.V., T.v.d.P.).
Alex F de VosFrom the Center for Experimental and Molecular Medicine (T.A.M.C., S.F.d.S., A.F.d.V., C.v.V., T.v.d.P.).
Anita E GrootemaatAcademic Medical Center, University of Amsterdam, The Netherlands; Electron Microscopy Center Amsterdam, Medical Biology, Academic Medical Center, The Netherlands (A.E.G., N.N.v.d.W.).
Nicole N van der WelAcademic Medical Center, University of Amsterdam, The Netherlands; Electron Microscopy Center Amsterdam, Medical Biology, Academic Medical Center, The Netherlands (A.E.G., N.N.v.d.W.).
Joris J T H RoelofsDepartment of Pathology (J.J.T.H.R.).
Jerry WareUniversity of Arkansas for Medical Sciences, Little Rock (J.W.).
Cornelis Van't VeerFrom the Center for Experimental and Molecular Medicine (T.A.M.C., S.F.d.S., A.F.d.V., C.v.V., T.v.d.P.).
Tom van der PollFrom the Center for Experimental and Molecular Medicine (T.A.M.C., S.F.d.S., A.F.d.V., C.v.V., T.v.d.P.).
University of Amsterdam · NLJisc · GBUniversity of Arkansas for Medical Sciences · US

Funding

TRANSGENIC ANALYSIS OF PLATELET RECEPTOR EXPRESSIONR01HL050545 · NHLBI · UNIV OF ARKANSAS FOR MED SCIS · PI WARE, JERRY · 1994 to 2012
$4.3M
NHLBI NIH HHS R01 HL050545
6 · The paper itself

Abstract

Objective- Nbeal2

Indexed as

AnimalsBlood PlateletsBlood ProteinsCD11b AntigenDisease Models, AnimalFemaleGray Platelet SyndromeHost-Pathogen InteractionsKlebsiella InfectionsKlebsiella pneumoniaeLipocalin-2MaleMatrix Metalloproteinase 9Mice, Inbred C57BLMice, KnockoutMonocytesadhesion receptorBlood ProteinsCD11b AntigenLcn2 protein, mouseLipocalin-2Matrix Metalloproteinase 9Mmp9 protein, mouseNbeal2 protein, mousePancreatic ElastasePeroxidasePlatelet Glycoprotein GPIb-IX Complexendotoxemiagray platelet syndromeinfectionneutrophilssepsis

Identifiers

PMID29930006
PMCPMC13142737
OpenAlexW2809079540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.