ArticleSurgery2018
Incidence and trends of cardiac complications in major abdominal surgery.
Article in Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Pooled it
- Prevalence of cardiometabolic outcomes in women who underwent salpingo-oophorectomy to prevent hereditary breast and ovarian cancer: a meta-analysis.Familial cancer · 2024Pooled it
- Incidence and Predictors of Perioperative Cardiac Events in Emergency Abdominal Surgeries: A Retrospective Study.Cureus · 2026Article
- Racial and Ethnic Disparities in Major Cardiovascular Events Following Non-Cardiovascular Surgeries.Journal of racial and ethnic health disparities · 2026Article
- Intraoperative Methadone Versus Epidural Analgesia for Perioperative Pain Management in Major Abdominal and Thoracic Surgery: A Retrospective Single-Center Study.Journal of clinical medicine · 2026Article
- Nomographic predictive models for complications after minimally invasive esophagectomy: Current status and future perspectives.World journal of gastrointestinal surgery · 2025Review
- Critical Care Management of Surgically Treated Gynecological Cancer Patients: Current Concepts and Future Directions.Cancers · 2025Review
- Benefit-finding experiences of liver transplant recipients who underwent perioperative extracorporeal membrane oxygenation treatment: a qualitative research.Frontiers in psychology · 2025Article
- Prognostic relevance of ventricular arrhythmias in surgical patients with gastrointestinal tumors.World journal of gastrointestinal oncology · 2024Article
- Evaluation of recipients with significant comorbidity - Patients with cardiovascular disease.Journal of hepatology · 2023Review
- The incidence and risk factors of perioperative cardiac complications in noncardiac major surgery in high-altitude areas: A prospective trial in Tibet autonomous region, China.Frontiers in cardiovascular medicine · 2023Article
- Results of emergency colectomy in nonagenarians and octogenarians previously labeled as prohibitive surgical risk.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Article
- The incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer in Japanese hospitals: A large-scale clinical study.Annals of gastroenterological surgery · 2022Article
- Association between tissue oxygenation and myocardial injury in patients undergoing major spine surgery: a prospective cohort study.BMJ open · 2021Observational
- Risk factors and therapeutic measures for postoperative complications associated with esophagectomy.Annals of medicine and surgery (2012) · 2020Review
- AUB-HAS2 Cardiovascular Risk Index: Performance in Surgical Subpopulations and Comparison to the Revised Cardiac Risk Index.Journal of the American Heart Association · 2020Article
- Impact of Age on Short- and Long-Term Outcomes after Pancreatoduodenectomy for Periampullary Neoplasms.Gastroenterology research and practice · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
introductionCardiovascular complications are the leading cause of death after noncardiac surgery. Major abdominal operations represent the largest category of procedures considered to have an increased risk of cardiovascular complications. The current aim was to examine trends in the incidence of mortality, perioperative myocardial infarction, and cardiac arrest to determine the presence of potential volume-outcome relationships.
methodsWe performed a retrospective analysis of the Nationwide Inpatient Sample for patients undergoing elective, open abdominal esophagectomy, gastrectomy, pancreatectomy, nephrectomy, hepatectomy, splenectomy, and colectomy (major abdominal surgery) during 2008-2014. Univariate and multivariate analyses were performed to determine the impact of operative volume on rates of myocardial infarction, cardiac arrest, and mortality.
resultsOf the 962,754 elective admissions for major abdominal surgery, 1.4% experienced in-hospital mortality, 0.7% myocardial infarction, and 0.35% cardiac arrest. Myocardial infarction and cardiac arrest were associated with a 24-fold increase in risk of perioperative mortality. Compared with institutions that have a very low volume of operations, those hospitals with larger volumes of operations had a decreased risk of cardiac arrest and incident mortality after cardiovascular complications, but the odds of myocardial infarction were greatest at higher operative-volume hospitals. The annual all-cause mortality and myocardial infarction rates decreased over time, but the incidence of cardiac arrest increased.
conclusionMyocardial infarction or cardiac arrest after major abdominal surgery increased the odds of mortality with superior rescue after cardiovascular complications at higher volume institutions. Across all US hospitals performing major abdominal surgery, the rate of cardiac arrest increased without a concomitant increase in myocardial infarction or mortality. Novel targets for risk modification of myocardial infarction and cardiac arrest as well as investigation of processes that facilitate rescue after these complications at higher operative-volume hospitals are needed to delineate quality improvement opportunities.
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Registered trials
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