ArticleBMC cardiovascular disorders2018
Predictors of aortic dilation in patients with coarctation of the aorta: evaluation with dual-source computed tomography.
Article in BMC cardiovascular disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 22 citations in OpenAlex.
- The Effect of Stenting on Post-Stenotic Dilatation in Coarctation of The Aorta.Pediatric cardiology · 2025Article
- Application of Computed Tomography Angiography in Preoperative Diagnosis of Coarctation of Aorta and Evaluation of Aortic Dilatation in Infants.Brazilian journal of cardiovascular surgery · 2024Article
- Computed tomography angiography assessment of the degree of simple coarctation of the aorta and its relationship with surgical outcome: A retrospective analysis.Frontiers in pediatrics · 2022Article
- Evaluation of the aorta in infants with simple or complex coarctation of the aorta using CT angiography.Frontiers in cardiovascular medicine · 2022Article
- Associations of exposure to secondhand smoke with hypertension risk and blood pressure values in adults.Environmental health and preventive medicine · 2021Article
- Aortic Dilatation in Patients With Bicuspid Aortic Valve.Frontiers in physiology · 2021Review
- A Review of Selected Adult Congenital Heart Diseases Encountered in Daily Practice.Current cardiology reviews · 2021Review
- Management of adults with coarctation of aorta.World journal of cardiology · 2020Review
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7 authors at 1 institution in 1 country.
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Abstract
backgroundCoarctation of aorta (CoA) may progressively develop aortic dilation at other site of the aorta and can lead to fatal aortic diseases. We aimed to evaluate the occurrence of aortic dilation and related predictors in patients with CoA using dual-source computed tomography (DSCT).
methodsFifty-three patients with CoA identified by DSCT were retrospectively reviewed. Aortic diameters were measured at six different levels and standardized as z-scores based on the square root of body surface area. Coarctation site-diaphragm ratio (CDR) was used to describe the degree of narrowing. A total of 26 patients were included in mild group (CDR > 50%) and 27 in severe group (CDR < 50%) according to the severity of coarctation. Student's t-test and Spearman correlation coefficients, univariate and multivariable logistic regression analyses were used to assess the risk factors including age, degree of narrowing and other malformations for aortic dilation.
resultsSevere group had significantly larger z-scores of ascending aorta (2.41 ± 0.39 vs. 2.10 ± 0.57, p < 0.05) and post-coarctation aorta (2.17 ± 0.48 vs. 1.68 ± 0.43, p < 0.001) compared with mild group. Degree of coarctation was associated with the z-scores of the ascending aorta (r = - 0.356, p < 0.05) and post-coarctation aorta (r = - 0.414, p < 0.05). Collateral circulation was related to the z-scores of ascending aorta (r = 0.375, p < 0.05). Increased severity of coarctation was independent predictor of ascending (odds ratio 7.46; 95% CI 1.19-46.76; p < 0.05) and post-coarctation aortic dilation(odds ratio 8.42; 95% CI 1.84-38.56; p < 0.05).
conclusionsAscending and post-coarctation aortic diameters or dilations were both associated with the degree of coarctation. By comprehensively evaluating the aortic diameters and associated malformations including collateral circulation, DSCT can aid in stratification of risk for aortic dilation in patients with CoA.
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