Evidence map›Paper›PMID 29929349›Full record

ReviewThe Korean journal of internal medicine2018

Neuropathic cancer pain: prevalence, pathophysiology, and management.

So Young Yoon, Jeeyoung Oh

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Korean journal of internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427058 (Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management), which is not on this map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05427058 narecruitingnot on this mapstarted 2024, after this paper: background citation

Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management: A Randomized Controlled Trial of Efficacy and Safety

TypeinterventionalSponsorUniversity of BrawijayaRan2024 to 2026Enrolled36ConditionsCervical Cancer, Endometrial CancerArmsSuperior Hypogastric Plexus Block, Ganglion Impar Block
3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Cancer pain.Nature reviews. Disease primers · 2026
    Review
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  10. Financial hardship and pain among cancer survivors: a French nationwide cross-sectional analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

So Young YoonDivision of Oncology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Jeeyoung OhDepartment of Neurology, Konkuk University School of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropathic cancer pain (NCP) is caused by nerve damage attributable to the cancer per se, and/or treatments including chemotherapy, radiotherapy, and surgery; the prevalence is reported to be as high as 40%. The etiologies of NCP include direct nerve invasion or nerve compression by the cancer, neural toxicity, chemotherapy, and radiotherapy. NCP is subdivided into plexopathy, radiculopathy, and peripheral neuropathies, among several other categories. The clinical characteristics of NCP differ from those of nociceptive pain in terms of both the hypersensitivity symptoms (burning, tingling, and an electrical sensation) and the hyposensitivity symptoms (numbness and muscle weakness). Recovery requires several months to years, even after recovery from injury. Management is complex; NCP does not usually respond to opioids, although treatments may feature both opioids and adjuvant drugs including antidepressants, anticonvulsants, and anti-arrhythmic agents, all of which improve the quality-of-life. This review addresses the pathophysiology, clinical characteristics and management of NCP, and factors rendering pain control difficult.

Indexed as

Cancer PainNeuralgiaAnalgesicsHumansPain ManagementPain MeasurementPain PerceptionPain ThresholdPrevalenceQuality of LifeRisk FactorsTreatment OutcomeAnalgesicsChemotherapy drugsNeoplasmsNeuralgia

Identifiers

PMID29929349
PMCPMC6234399

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.