Evidence map›Paper›PMID 29928770›Full record

ArticleThe Journal of physiology2018

Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca

Q Wen, K Gandhi, Rebecca A Capel, G Hao, C O'Shea, G Neagu, S Pearcey, D Pavlovic, Derek A Terrar, J Wu and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Optical mapping and optogenetics in cardiac electrophysiology research and therapy: a state-of-the-art review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Review
  4. Article
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  6. Article
  7. Review
  8. Article
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  10. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  11. Article
  12. Article
  13. Review
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  15. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Q WenInstitution of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
K GandhiMedical School, University of Verona, Verona, Italy.
Rebecca A CapelDepartment of Pharmacology, University of Oxford, Oxford, UK.
G HaoKey Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 6400, China.
C O'SheaInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.
G NeaguDepartment of Pharmacology, University of Oxford, Oxford, UK.
S PearceyDepartment of Pharmacology, University of Oxford, Oxford, UK.
D PavlovicInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0002-3171-3551
Derek A TerrarDepartment of Pharmacology, University of Oxford, Oxford, UK.
J WuInstitution of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
G FaggianMedical School, University of Verona, Verona, Italy.ORCID 0000-0001-5371-5761
Patrizia CamellitiSchool of Biosciences and Medicine, University of Surrey, Guildford, UK.ORCID 0000-0002-1346-8089
M LeiDepartment of Pharmacology, University of Oxford, Oxford, UK.ORCID 0000-0002-0928-341X
University of Oxford · GBSouthwest Medical University · CNUnion Hospital · CNUniversity of Birmingham · GBUniversity of Verona · ITUniversity of Surrey · GB

Funding

British Heart Foundation FS/17/33/32931British Heart Foundation PG/11/59/29006British Heart Foundation PG/12/21/29473British Heart Foundation PG/14/80/31106British Heart Foundation PG/16/67/32340British Heart Foundation PG/17/55/33087Medical Research Council G1002082Medical Research Council G1002647
6 · The paper itself

Abstract

key pointsA robust cardiac slicing approach was developed for optical mapping of transmural gradients in transmembrane potential (V ABSTRACT: Transmural and regional gradients in membrane potential and Ca

Indexed as

Calcium SignalingMembrane PotentialsAnimalsEndocardiumHeartHeart VentriclesMiceOptical ImagingPericardiumcardiac sliceselectrophysiological heterogeneitymurine heartoptical imaging

Identifiers

PMID29928770
PMCPMC6117587
OpenAlexW2808892522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.