Evidence map›Paper›PMID 29928701›Full record

ReviewClinical and translational radiation oncology2018

Adjuvant chemoradiation for gastric carcinoma: State of the art and perspectives.

A Schernberg, E Rivin Del Campo, B Rousseau, O Matzinger, M Loi, P Maingon, F Huguet

Abstract readReview
In one paragraph

Review in Clinical and translational radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Overview of Chemotherapy for Gastric Cancer.Journal of clinical medicine · 2023
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A SchernbergService d'Oncologie Radiothérapie, Hôpital Tenon, Hôpitaux Universitaires Est Parisien, Paris, France.
E Rivin Del CampoService d'Oncologie Radiothérapie, Hôpital Tenon, Hôpitaux Universitaires Est Parisien, Paris, France.
B RousseauService d'Oncologie Médicale, Hôpital Henri Mondor, Paris, France.
O MatzingerRadiotherapy Department, Cancer Center, Riviera-Chablais Hospital, Vevey, Switzerland.
M LoiDepartment of Radiotherapy, Erasmus MC Cancer Institute, PO Box 2040, 3000 CA Rotterdam, The Netherlands.
P MaingonService d'Oncologie Radiothérapie, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, Paris, France.
F HuguetService d'Oncologie Radiothérapie, Hôpital Tenon, Hôpitaux Universitaires Est Parisien, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An estimated 990,000 new cases of gastric cancer are diagnosed worldwide each year. Surgical excision, the only chance for prolonged survival, is feasible in about 20% of cases. Even after surgery, the median survival is limited to 12 to 20 months due to the frequency of locoregional and/or metastatic recurrences. This led to clinical trials associating surgery with neoadjuvant or adjuvant treatments to improve tumor control and patient survival. The most studied modalities are perioperative chemotherapy and adjuvant chemoradiotherapy. To date, evidence has shown a survival benefit for postoperative chemoradiotherapy and for perioperative chemotherapy. Phase III trials are ongoing to compare these two modalities. The aim of this review is to synthesize current knowledge about adjuvant chemoradiotherapy in the management of gastric adenocarcinoma, and to consider its prospects by integrating modern radiotherapy techniques.

Indexed as

5FU, 5-fluorouracil5FU-LV, 5-fluorouracil leucovorinAdenocarcinomaAdjuvant therapyChemoradiotherapyCRT, chemoradiotherapyCT, chemotherapyDCF, Doxorubicin Cisplatin 5-fluorouracilECF, Epirubicin Cisplatin 5-fluorouracilECX, Epirubicin Cisplatin CapecitabinFOLFOX, 5-fluorouracil oxaliplatinFUFOL, bolus 5-fluorouracil followed by leucovorin over 15 minutesGastric cancerIMRTIMRT, intensity modulated radiation therapyLV, leucovorinRT, radiation therapyXELOX, capecitabin oxaliplatine

Identifiers

PMID29928701
PMCPMC6008627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.