Evidence map›Paper›PMID 29928645›Full record

ArticleCase reports in nephrology and dialysis

Bile Cast Nephropathy: The Unknown Dangers of Online Shopping.

Andrea Fisler, Tobias Breidthardt, Nadine Schmidlin, Helmut Hopfer, Michael Dickenmann, Katrin König, Patricia Hirt-Minkowski

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in nephrology and dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Bile Cast Nephropathy an Important Biliary Culprit of Kidney Injury.Journal of community hospital internal medicine perspectives · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrea FislerTransplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Tobias BreidthardtDivision of Internal Medicine, University Hospital Basel, Basel, Switzerland.
Nadine SchmidlinDivision of Internal Medicine, University Hospital Basel, Basel, Switzerland.
Helmut HopferInstitute for Pathology, University Hospital Basel, Basel, Switzerland.
Michael DickenmannTransplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Katrin KönigTransplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Patricia Hirt-MinkowskiTransplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal dysfunction in the setting of cholestatic liver disease is multifactorial but most often due to decreased kidney perfusion from intravascular volume depletion, acute tubular injury/necrosis, and hepatorenal syndrome. Drug-induced hepatotoxicity may be associated with a cholestatic injury pattern. We report a case of a 56-year-old man with a diagnosis of bile cast nephropathy, as a complication of drug-induced severe hyperbilirubinemia due to the abuse of intramuscular anabolic steroids bought on the internet to increase muscular mass for bodybuilding training. Kidney biopsy showed the histological pattern of diffuse potentially reversible tubular damage with intratubular bile casts obstructing the renal tubules. The patient developed acute kidney injury and needed dialysis treatment for 4 weeks until renal function recovered. The severity of the kidney injury and the requirement of hemodialysis observed in our patient are unique and have not been previously described. As full recovery of renal function is suspected with decreasing bilirubin levels, early recognition and treatment of the underlying disease is essential.

Indexed as

Acute kidney injuryAnabolic steroidsBile cast nephropathyCholestatic jaundiceHyperbilirubinemia

Identifiers

PMID29928645
PMCPMC6006645
OpenAlexW2806695898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.