Evidence map›Paper›PMID 29928607›Full record

ArticleQuantitative imaging in medicine and surgery2018

Risk factors for poor outcome in posterior reversible encephalopathy syndrome: systematic review and meta-analysis.

Zheng Chen, Gang Zhang, Alexander Lerner, An-Hui Wang, Bo Gao, Jie Liu

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Cross-sectional analysis of posterior reversible encephalopathy syndrome in pregnant women with and without HELLP syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  13. Factors affecting hospitalization, imaging severity, and complications in posterior reversible encephalopathy syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zheng ChenDepartment of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.
Gang ZhangDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai 264000, China.
Alexander LernerDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
An-Hui WangDepartment of Epidemiology, School of Public Health, The Fourth Military Medical University, Xi'an 710032, China.
Bo GaoDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai 264000, China.
Jie LiuDepartment of Neurosurgery, Yantai Yuhuangding Hospital, Yantai 264000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe roles of clinical etiology and symptoms, imaging findings and biochemical parameters in predicting the prognosis of posterior reversible encephalopathy syndrome (PRES) have not been well-characterized. We perform a meta-analysis of all published studies to assess the value of various risk factors in predicting the prognosis of PRES.

methodsSearches of the PubMed, EMBASE, Cochrane Library, and Web of Science databases were performed to identify the eligible studies. The odds ratios (ORs) with their corresponding 95% confidence interval (CI) for related risk factors were used to calculate the pooled estimates of the outcomes.

resultsSix studies with 448 cases were included in the meta-analysis. Hemorrhage was associated with high risk for poor outcome in patients with PRES. Toxemia of pregnancy (pre-eclampsia/eclampsia) was associated with improved outcome in PRES patients. Cytotoxic edema was noted to be related to poor outcome, but did not show statistical significance. The pooled OR for hemorrhage, pre-eclampsia/eclampsia, cytotoxic edema was 4.93 (95% CI: 3.94-6.17; P<0.00001), 0.24 (95% CI: 0.15-0.40; P<0.00001) and 2.59 (95% CI: 0.84-7.99; P=0.10), respectively.

conclusionsPRES patients with hemorrhage or cytotoxic edema are likely to have poor outcomes. Pre-eclampsia/eclampsia is associated with reduced risk of poor outcome in patients with PRES.

Indexed as

hemorrhagemeta-analysisoutcomePosterior reversible encephalopathy syndrome (PRES)

Identifiers

PMID29928607
PMCPMC5989088

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.