Evidence map›Paper›PMID 29928511›Full record

ArticleCell discovery2018

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements.

Dang Vinh Do, Bernhard Strauss, Engin Cukuroglu, Iain Macaulay, Keng Boon Wee, Tim Xiaoming Hu, Ruiz De Los Mozos Igor, Caroline Lee, Andrew Harrison, Richard Butler and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cell discovery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
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  8. hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  11. BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

Dang Vinh Do1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.
Bernhard Strauss1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.
Engin Cukuroglu3Computational and Systems Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore, 138672 Singapore.
Iain Macaulay4Earlham Institute, Norwich Research Park, Norwich, NR4 7UH UK.
Keng Boon Wee5Department Fluid Dynamics, Institute of High Performance Computing, 1 Fusionopolis Way, Singapore, 138632 Singapore.
Tim Xiaoming HuEMBL European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, Cambridge, UK.
Ruiz De Los Mozos Igor8Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.ORCID 0000-0003-4097-6422
Caroline Lee1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.
Andrew Harrison1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.ORCID 0000-0002-3778-8415
Richard Butler1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.ORCID 0000-0002-3885-1332
Sabine Dietmann9Wellcome Trust Medical Research Council Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR UK.
Ule Jernej8Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.ORCID 0000-0002-2452-4277
John Marioni8Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Christopher W J Smith12Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.ORCID 0000-0002-2753-3398
Jonathan Göke3Computational and Systems Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore, 138672 Singapore.ORCID 0000-0002-0825-4991
M Azim Surani1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.
University of Cambridge · GBGenome Institute of Singapore · SGInstitute of Molecular Medicine · INEuropean Bioinformatics Institute · GBInstitute of High Performance Computing · SGNorwich Research Park · GBWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Cancer Research UK 22231Wellcome Trust 209475/Z/17/Z
6 · The paper itself

Abstract

The RNA-binding protein SRSF3 (also known as SRp20) has critical roles in the regulation of pre-mRNA splicing. Zygotic knockout of

Identifiers

PMID29928511
PMCPMC6006335
OpenAlexW2807819333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.