Evidence map›Paper›PMID 29928370›Full record

ArticleOncology letters2018

Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.

Makoto Osanai, Akira Takasawa, Kumi Takasawa, Masaki Murata, Norimasa Sawada

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Makoto OsanaiDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8556, Japan.
Akira TakasawaDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8556, Japan.
Kumi TakasawaDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8556, Japan.
Masaki MurataDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8556, Japan.
Norimasa SawadaDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8556, Japan.
Sapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated expression of the retinoic acid-metabolizing enzyme cytochrome P450 26A1 (CYP26A1) has been demonstrated to have an oncogenic function in carcinogenesis. In order to address the oncogenic capacity of CYP26A1

Indexed as

7,12-dimethylbenz[a]anthracenecytochrome P450 26A1retinoic acidretinoic acid-metabolizing enzymeskin carcinogenesistransgenic mice

Identifiers

PMID29928370
PMCPMC6004672
OpenAlexW2800182237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.