ArticleOncology letters2018
Gene microarray analysis of the circular RNAs expression profile in human gastric cancer.
Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- ATF4-mediated circTDRD3 promotes gastric cancer cell proliferation and metastasis by regulating the miR-891b/ITGA2 axis and AKT signaling pathway.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023Article
- Functions of circular RNAs and their potential applications in gastric cancer (Review).Oncology letters · 2023Review
- Circ_0067997 boosted the growth while repressed the apoptosis of SGC-7901/DDP cells via repressing miR-615-5p/AKT1 pathway.Cancer biomarkers : section A of Disease markers · 2023Article
- The circular RNA hsa_circ_000780 as a potential molecular diagnostic target for gastric cancer.BMC medical genomics · 2021Article
- Hsa_circ_0076305 induces migration-proliferation dichotomy in gastric cancer.Oncology letters · 2021Article
- Identification of novel biomarkers, MUC5AC, MUC1, KRT7, GAPDH, CD44 for gastric cancer.Medical oncology (Northwood, London, England) · 2020Article
- Circular RNAs and gastrointestinal cancers: Epigenetic regulators with a prognostic and therapeutic role.Critical reviews in oncology/hematology · 2020Review
- Identification of Key Genes and Prognostic Analysis between Chromophobe Renal Cell Carcinoma and Renal Oncocytoma by Bioinformatic Analysis.BioMed research international · 2020Article
- Circular RNAs: from biogenesis and function to diseases.Chinese medical journal · 2019Review
- Role of circular RNAs in gastric cancer: Recent advances and prospects.World journal of gastrointestinal oncology · 2019Review
- Recent advances in gastric cancer early diagnosis.World journal of gastroenterology · 2019Review
- circZNF609 promotes the proliferation and migration of gastric cancer by sponging miR-483-3p and regulating CDK6.OncoTargets and therapy · 2019Article
- Functional Site Discovery From Incomplete Training Data: A Case Study With Nucleic Acid-Binding Proteins.Frontiers in genetics · 2019Article
- The emerging role of circular RNAs in gastric cancer.American journal of cancer research · 2018Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human gastric cancer is a common malignant neoplasm of the digestive system and represents a threat to human health worldwide. The mechanisms underlying gastric cancer germination and development are not yet fully understood. Circular RNAs (circRNAs) serve crucial roles in various physiological and pathological processes, particularly cancer. However, few studies have focused on the mechanisms involving circRNAs in gastric cancer. Therefore the present study set out to identify the differentially expressed circRNAs in gastric cancer. Three specimens of gastric cancer and normal gastric tissue were selected and circRNA microarray analysis was performed to detect the differentially expressed circRNAs. The changes in circRNAs were confirmed by reverse transcription-quantitative polymerase chain reaction analysis. A total of 347 upregulated and 603 downregulated circRNAs (fold-change, >2.0) were identified in gastric cancer compared with the normal gastric tissue. A total of 20 selected circRNAs were dysregulated during gastric cancer, which suggests their potential role in gastric cancer. The present study identified circRNAs in the expression profile of human gastric cancer that were potentially involved in the underlying molecular mechanisms of its development.
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