Evidence map›Paper›PMID 29928343›Full record

ArticleOncology letters2018

Sesquiterpene lactone 6-O-angeloylplenolin reverses vincristine resistance by inhibiting YB-1 nuclear translocation in colon carcinoma cells.

Changlong Li, Hezhen Wu, Yanfang Yang, Jianwen Liu, Zhenwen Chen

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. YB-1 activating cascades as potential targets in KRAS-mutated tumors.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Review
  3. Review
  4. Review
  5. Natural and Synthetic Lactones Possessing Antitumor Activities.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Arnicolide D, from the herbMolecules (Basel, Switzerland) · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Changlong LiSchool of Basic Medical Science, Capital Medical University, Beijing 100069, P.R. China.
Hezhen WuKey Laboratory of Resources and Chemistry of Chinese Medicine of the Ministry of Education, Hubei University of Chinese Medicine, Wuhan, Hubei 430061, P.R. China.
Yanfang YangKey Laboratory of Resources and Chemistry of Chinese Medicine of the Ministry of Education, Hubei University of Chinese Medicine, Wuhan, Hubei 430061, P.R. China.
Jianwen LiuSchool of Pharmacy, East China University of Science and Technology, Shanghai 200237, P.R. China.
Zhenwen ChenSchool of Basic Medical Science, Capital Medical University, Beijing 100069, P.R. China.
Capital Medical University · CNHubei University of Chinese Medicine · CNEast China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance (MDR) is a major obstacle to cancer chemotherapy efficacy. In the present study, 6-O-angeloylplenolin repressed the overexpression of ATP binding cassette subfamily B member 1 (

Indexed as

6-O-angeloylplenolincolon carcinomaMDR1multidrug resistancenuclear translocationvincristineYB-1

Identifiers

PMID29928343
PMCPMC6004700
OpenAlexW2802527862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.