Evidence map›Paper›PMID 29928273›Full record

ReviewFrontiers in immunology2018

Neurological Disease in Lupus: Toward a Personalized Medicine Approach.

Sarah McGlasson, Stewart Wiseman, Joanna Wardlaw, Neeraj Dhaun, David P J Hunt

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Sarah McGlassonMRC Institute of Genetics and Molecular Medicine, Edinburgh, United Kingdom.
Stewart WisemanThe UK Dementia Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Joanna WardlawThe UK Dementia Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Neeraj DhaunCentre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
David P J HuntMRC Institute of Genetics and Molecular Medicine, Edinburgh, United Kingdom.
University of Edinburgh · GBMRC Institute of Genetics and Molecular Medicine · GBThe Queen's Medical Research Institute · GBUK Dementia Research Institute · GB

Funding

MRF_ MRF-159-0001-ELP-HUNTThe Dunhill Medical Trust R380R/1114Wellcome TrustWellcome Trust WT101153MA
6 · The paper itself

Abstract

The brain and nervous system are important targets for immune-mediated damage in systemic lupus erythematosus (SLE), resulting in a complex spectrum of neurological syndromes. Defining nervous system disease in lupus poses significant challenges. Among the difficulties to be addressed are a diversity of clinical manifestations and a lack of understanding of their mechanistic basis. However, despite these challenges, progress has been made in the identification of pathways which contribute to neurological disease in SLE. Understanding the molecular pathogenesis of neurological disease in lupus will inform both classification and approaches to clinical trials.

Indexed as

AnimalsBiomarkersCombined Modality TherapyDiagnosis, DifferentialDiagnostic ImagingDisease ManagementDisease SusceptibilityHumansLupus Erythematosus, SystemicNervous System DiseasesPrecision MedicineBiomarkersinterferon type Ilupus erythematosusneurolupuspersonalized medicinesystemictargeted therapy

Identifiers

PMID29928273
PMCPMC5997834
OpenAlexW2805872240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.