ArticlePloS one2018
Factors affecting the clinical relevance of Corynebacterium striatum isolated from blood cultures.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Clinical characteristics, antimicrobial resistance patterns, and outcomes of Corynebacterium bacteremia: a 15-year retrospective study.BMC infectious diseases · 2025Article
- Clinical and Molecular Advances on the Black YeastInternational journal of molecular sciences · 2025Review
- Metagenomic next-generation sequencing for the diagnosis of Corynebacterium striatum meningitis: case report and literature review.BMC neurology · 2025Review
- Rising prevalence and drug resistance ofFrontiers in cellular and infection microbiology · 2024Review
- Epidemiological Investigation of Hospital Transmission of Corynebacterium striatum Infection by Core Genome Multilocus Sequence Typing Approach.Microbiology spectrum · 2023Article
- Cholesteatoma has an altered microbiota with a higher abundance ofLaryngoscope investigative otolaryngology · 2022Article
- Article
- Clinical Characteristics of Corynebacterium Bacteremia Caused by Different Species, Japan, 2014-2020.Emerging infectious diseases · 2021Review
- Wide spread and diversity of mutation in the gyrA gene of quinolone-resistant Corynebacterium striatum strains isolated from three tertiary hospitals in China.Annals of clinical microbiology and antimicrobials · 2021Article
- Treat Me Well or Will Resist: Uptake of Mobile Genetic Elements Determine the Resistome ofInternational journal of molecular sciences · 2021Review
- Bone and Joint Infection InvolvingFrontiers in medicine · 2020Article
- Cytokine Levels in thePolish journal of microbiology · 2019Article
- Whole-Genome Sequencing Reveals a Prolonged and Persistent Intrahospital Transmission of Corynebacterium striatum, an Emerging Multidrug-Resistant Pathogen.Journal of clinical microbiology · 2019Article
- A Novel Approach to Study the Effect of Ciprofloxacin on Biofilms ofPolish journal of microbiologyArticle
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to identify clinical or microbiological factors affecting the clinical relevance of Corynebacterium striatum isolated from blood cultures. A total of 64 isolates from 51 patients identified as C. striatum by matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing were assessed. More than two blood cultures were positive in 25 (48.1%) patients. Diabetes, solid tumor, and a history of previous exposure to antibiotics were more common in patients with multiple positive blood cultures. Charlson comorbidity scores were also higher, and more isolates were recovered after 48 hours of hospital stay in patients with multiple positive blood cultures. Strains recovered from patients with multiple positive blood cultures produced significantly more biofilm. Based on multilocus sequence typing (MLST), sequence type (ST) 20 (31.3%) was the most dominant, followed by ST2 (20.3%) and ST23 (10.9%). There was no relationship between the number of positive blood culture sets and sequence typing. In multivariate analyses, Carlson comorbidity score (odds ratio [OR], 1.91; 95% confidence interval [CI], 1.09-3.36; P = 0.03) and biofilm formation were associated with multiple positive blood cultures (OR, 17.43; 95% CI, 3.71-81.91; P = 0.03). This study provides evidence that the biofilm phenotype could contribute to determining the clinical significance of C. striatum in patients with severe underlying conditions. The predominance of certain STs suggests the relatedness of C. striatum infection and the nosocomial environment.
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