ArticlePloS one2018
Molecular characterization and antimicrobial susceptibility pattern of Streptococcus agalactiae isolated from clinical mastitis in dairy cattle.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Veterinary macrolides againstFrontiers in veterinary science · 2026Pooled it
- Dairy FarmPathogens (Basel, Switzerland) · 2026Article
- Comprehensive Prevention and Control of Mastitis in Dairy Cows: From Etiology to Prevention.Veterinary sciences · 2025Review
- Nanoparticles as an alternative treatment for bovine mastitis-A review.Animal bioscience · 2025Article
- Virulence factors of bovine mastitis pathogens: distribution, pathogenesis, and emerging vaccines targeting virulence factors: a literature review.Frontiers in veterinary science · 2025Review
- Antibiotic Resistance and Presence of Persister Cells in the Biofilm-like Environments inAntibiotics (Basel, Switzerland) · 2024Article
- Occurrence of antimicrobial-resistant bovine mastitis bacteria in Sakon Nakhon, Thailand.Veterinary world · 2024Article
- Long-Term Co-Circulation of Host-Specialist and Host-Generalist Lineages of Group BAntibiotics (Basel, Switzerland) · 2024Article
- Characterization of Virulence Factors and Antimicrobial Susceptibility ofAnimals : an open access journal from MDPI · 2024Article
- Article
- Characteristics of Streptococcus agalactiae belonging to CC103 clone circulating among dairy herds and pregnant women in Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Genotypic and antimicrobial susceptibility ofFrontiers in veterinary science · 2023Article
- Antimicrobial Resistance and Virulence Genes ofJournal of veterinary research · 2022Article
- Article
- Molecular epidemiology, drug resistance, and virulence gene analysis ofFrontiers in cellular and infection microbiology · 2022Article
- The landscape of antimicrobial resistance in the neonatal and multi-host pathogen group BFrontiers in microbiology · 2022Article
- Proteomic Characterization of Antibiotic Resistance inInternational journal of molecular sciences · 2021Article
- Evidence of Common Isolates ofFrontiers in microbiology · 2021Article
- Multidrug Resistance and Molecular Characterization ofFrontiers in cellular and infection microbiology · 2021Article
- Epidemiology and Classification of Mastitis.Animals : an open access journal from MDPI · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objectives of this study were to: (a) genotypically characterize Streptococcus agalactiae isolates recovered from clinical mastitis (CM) cases in dairy cows and, (b) determine the association of antimicrobial susceptibility (AMS) and genotypes of Strep. agalactiae clustered according to the genetic similarity. A total of 89 Strep. agalactiae isolates recovered from bovine CM were genotyped using random amplified polymorphic DNA (RAPD) analysis. In addition, the AMS of the isolates was determined using a commercial broth microdilution test composed of 10 antimicrobials (penicillin, ampicillin, oxacillin, cephalothin, ceftiofur, penicillin/novobiocin, erythromycin, pirlimycin, tetracycline, and sulfadimethoxine). Descriptive analysis was used to report the frequency of RAPD-types and genotypic clusters within herd, housing system, season and CM severity scores. The minimal antimicrobial concentrations that inhibited 50% (MIC50) and 90% (MIC90) of the isolates were calculated and survival analysis was completed to verify the differences of AMS among genotypic clusters. Results of RAPD showed a great genotypic diversity of Strep. agalactiae (45 RAPD-types) and three clusters (Ia, Ib and II) were created based on the genetic similarity among genotypes. After clustering, a high genetic similarity was observed within and between herds. Overall, Strep. agalactiae showed high susceptibility to most antimicrobials, except to tetracycline and erythromycin. Differences in the AMS among clusters were observed for ampicillin, ceftiofur, erythromycin, pirlimycin, sulfadimethoxine and tetracycline. In conclusion, Strep. agalactiae is still highly susceptible to most antimicrobials, although differences in susceptibility to certain antimicrobials were observed among genotypic clusters.
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