Evidence map›Paper›PMID 29928008›Full record

ArticlePloS one2018

Understanding willingness to use oral pre-exposure prophylaxis for HIV prevention among men who have sex with men in China.

Xia Wang, Adam Bourne, Pulin Liu, Jiangli Sun, Thomas Cai, Gitau Mburu, Matteo Cassolato, Bangyuan Wang, Wang Zhou

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Xia WangWuhan Centers for Disease Prevention & Control, Wuhan, Hubei, China.
Adam BourneAustralian Research Centre in Sex, Health & Society, La Trobe University, Melbourne, Australia.
Pulin LiuWuhan Centers for Disease Prevention & Control, Wuhan, Hubei, China.
Jiangli SunAIDS Care China, Kunming, Yunnan, China.
Thomas CaiAIDS Care China, Nanning, Guangxi, China.
Gitau MburuInternational HIV/AIDS Alliance, Brighton, United Kingdom.
Matteo CassolatoInternational HIV/AIDS Alliance, Brighton, United Kingdom.
Bangyuan WangInternational HIV/AIDS Alliance, Brighton, United Kingdom.
Wang ZhouWuhan Centers for Disease Prevention & Control, Wuhan, Hubei, China.ORCID 0000-0002-4098-9306
International HIV/AIDS Alliance · GBWuhan Center for Disease Control and Prevention · CNLa Trobe University · AUYunnan Provincial Infectious Disease Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral pre-exposure prophylaxis (PrEP) is recommended as an additional prevention choice for men who have sex with men (MSM) at substantial risk of HIV. The aim of this study was to evaluate the extent, and reasons, for MSM's willingness to use oral PrEP in Wuhan and Shanghai, China.

methodsBetween May and December 2015, a cross-sectional survey was conducted among 487 MSM recruited through snowball sampling in physical locations frequented by MSM and through social media applications. Exploratory factor analysis was used to group reasons for being willing or not willing to use PrEP. Chi-square tests were used to explore bivariate associations between groupings of reasons for being willing or unwilling to use PrEP, and key sociodemographic and sexual-behavioral characteristics of MSM.

resultsOverall, 71.3% of respondents were willing to use PrEP. The most commonly reported reasons for being willing to use PrEP were preventing HIV infection (91.6%), taking responsibility for own sexual health (72.6%) and protecting family members from harm (59.4%). The main reasons for being unwilling to use PrEP were being worried about side effects (72.9%), the necessity of taking PrEP for long periods of time (54.3%) and cost (40.4%). Individual characteristics that influenced the type of reasons given for being willing or unwilling to use PrEP included being married to a woman, having a regular sex partner, rates of condom use with regular and casual sex partners, and the number of casual sex partners.

conclusionThe introduction of PrEP in China could benefit from promotion campaigns that emphasize its role in preventing HIV infection, in taking responsibility for own sexual health, and in protecting family members from potential harm. To reduce uptake barriers, it will be essential to provide accurate information to potential PrEP users about the mild and short-term nature of side effects, and the possibility of taking PrEP only during particular periods of life when the risk of HIV exposure might be highest.

Indexed as

Health Knowledge, Attitudes, PracticePatient Acceptance of Health CarePre-Exposure ProphylaxisAdolescentAdultChinaCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedSafe SexSexual and Gender MinoritiesYoung Adult

Identifiers

PMID29928008
PMCPMC6013122
OpenAlexW2808761516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.