Evidence map›Paper›PMID 29926995›Full record

ArticleJournal of clinical laboratory analysis2018

Prevalence of combined and noncombined dyslipidemia in an Iranian population.

Susan Darroudi, Maryam Saberi-Karimian, Maryam Tayefi, Soheil Arekhi, Ali Motamedzadeh Torghabeh, Seyed Mohammad Reza Seyedzadeh Sani, Mohsen Moohebati, Alireza Heidari-Bakavoli, Mahmoud Ebrahimi, Mahmoud Reza Azarpajouh and 9 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04977089 (Study of Lipid Profile of Patients With Chronic Coronary Syndromes at Sohag University Hospital), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04977089 unknown statusnot on this mapstarted 2020, after this paper: background citation

Study of Lipid Profile of Patients With Chronic Coronary Syndromes at Sohag University Hospital

TypeobservationalSponsorSohag UniversityRan2020 to 2021Enrolled100ConditionsIschemic Heart Disease, DyslipidemiasArmslipid profile test .
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

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  20. Association between qat chewing and dyslipidaemia among young males.Journal of Taibah University Medical Sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Susan DarroudiStudent Research Committee, Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID http://orcid.org/0000-0002-5377-729X
Maryam Saberi-KarimianStudent Research Committee, Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam TayefiClinical Research Unit, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
Soheil ArekhiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
Ali Motamedzadeh TorghabehStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
Seyed Mohammad Reza Seyedzadeh SaniStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
Mohsen MoohebatiCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza Heidari-BakavoliCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud EbrahimiCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud Reza AzarpajouhCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad SafarianBiochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon A FernsDepartment of Biostatistics & Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Habibollah EsmaeiliDepartment of Biostatistics & Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Reza ParizadehMetabolic Syndrome Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Naghme MokhberCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Adeleh MahdizadehCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali Asghar MahmoudiHead of the Health Center N.2 of Mashhad, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir Hossein SahebkarNeurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID http://orcid.org/0000-0002-8656-1444
Majid Ghayour-MobarhanCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IR

Funding

Mashhad University of Medical Sciences
6 · The paper itself

Abstract

backgroundCombination of dyslipidemic phenotypes, including elevated plasma levels of low-density lipoprotein cholesterol (LDL-C), elevated plasma triglycerides (TG), and decreased low-density lipoprotein cholesterol (HDL-C) concentrations, is important because of the association of individual phenotypes with increased risk of cardiovascular disease (CVD). We investigated the prevalence of combined dyslipidemias and their effects on CVD risk in an Iranian large population.

methodA total of 9847 individuals were recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study. Anthropometric parameters and biochemical indices were measured in all of the subjects. Different types of combined dyslipidemias including high TG + low HDL-C, high TG + low HDL-C + high LDL-C, low HDL-C + high LDL-C, high TG + high LDL-C, and finally high TG + high LDL-C + low HDL-C were considered. Ten-year CVD risk was calculated using the QRISK2 risk algorithm and adjustments were made as suggested by the Joint British Societies' (JBS2). Logistic regression analyses were performed to determine the association between different combined dyslipidemias and categorical QRISK.

resultsA total of 3952 males and 5895 females were included in this current study. Among the included subjects, 83.4% had one form of dyslipidemia, and 16.6% subjects were not dyslipidemic. The mean age was 48.88 ± 7.9 and 47.02 ± 8.54 years for dyslipidemic and nondyslipidemic groups, respectively. The results showed that the frequency of dyslipidemia was 98%, 87.1%, and 90% in subjects with metabolic syndrome, CVD, and diabetes, respectively. Our results suggested that around 15.7% of study population were at 10 years CVD risk (high ≥20) and it was higher in men than women (P < .001). Moreover, risk of CVD was higher in TG↑ & HDL↓ & LDL↑ group than other groups.

conclusionPrevalence of dyslipidemia was 83.4% among Iranian adults. The results showed that individuals with increased plasma TG and LDL-C, and low HDL-C levels had the highest 10 years CVD risk compared to other combined dyslipidemic phenotypes.

Indexed as

AdultCardiovascular DiseasesCohort StudiesDiabetes ComplicationsDyslipidemiasFemaleHumansIranLipoproteinsMaleMiddle AgedPrevalenceRisk FactorsLipoproteinscardiovascular diseasediabetes mellitusdyslipidemiaIran

Identifiers

PMID29926995
PMCPMC6816872
OpenAlexW2809641250

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.