ArticleInternational ophthalmology2019
Changes in ocular surface status after phacoemulsification in patients with senile cataract.
Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04812951 (Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Dry eye post-cataract surgery: a systematic review and meta-analysis.BMC ophthalmology · 2025Pooled it
- Bridging the gap in managing dry eye disease: a consensus report by the Taiwan society of cataract and refractive surgeons.BMC ophthalmology · 2024Guideline
- The effects of povidone-ıodine and chlorhexidine gluconate on the ocular surface after phacoemulsification cataract surgery.International ophthalmology · 2025Trial
- Trial
- Trial
- Assessment of the eye surface and subjective symptoms after using 0.1% dexamethasone drops with and without preservatives in patients after cataract surgery.Scientific reports · 2023Trial
- Trehalose/sodium hyaluronate eye drops in post-cataract ocular surface disorders.International ophthalmology · 2021Trial
- Intraoperative Use of a Topical Anesthetic Gel Versus Balanced Salt Solution During Cataract Surgery: Effects on Corneal Structure and Ocular Surface.Journal of clinical medicine · 2026Article
- Management of Dry Eye Disease Pre- and Post-Cataract Surgery: A Personalized Approach.Journal of personalized medicine · 2026Review
- Comparison of clinical and inflammatory markers for dry eye disease following phacoemulsification and manual small incision cataract surgery (MSICS).Scientific reports · 2026Article
- A Practical Approach for Optimizing Ocular Surface Status Before Cataract Surgery to Improve Visual Outcomes and Reduce the Risk of Postoperative Dry Eye.Ophthalmology and therapy · 2025Review
- Tissue Damage on Ocular Surface After Combined Phacoemulsification with Limbal Relaxing Incision Compared with Standard Phacoemulsification.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Ocular surface disease following LASIK and cataract surgery: a review of their interrelated complications.Frontiers in medicine · 2025Review
- The impact of cataract surgery on tear film physiology: signs and symptoms, progression and treatment.Frontiers in medicine · 2025Review
- The Mid-Term Effect of Preservative-Free Artificial Tears Containing Hyaluronic Acid on Dry Eye Incidence after Cataract Surgery: A Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2024Article
- Tear film assessment before and after phacoemulsification in patients with age-related cataracts.BMC ophthalmology · 2024Observational
- Ocular surface parameter changes in the untreated fellow eye after unilateral cataract surgery with short-term administration of anti-inflammatory eye drops.Scientific reports · 2024Article
- A Preservative-Free Approach - Effects on Dry Eye Signs and Symptoms After Cataract Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Clinical Outcomes of Cataract Surgery in Patients with Sjögren's Syndrome.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the signs and symptoms of dry eye after phacoemulsification; effects on the status of ocular surface using impression cytology; and associated risk factors.
methodsProspective study included 50 eyes (50 patients) with no dry eye signs or symptoms, who underwent clear corneal phacoemulsification for senile cataract. Dry eye indices used included Ocular Surface Disease Index scoring, Schirmer I test, tear break up time, tear meniscus height, corneal fluorescein staining, lissamine green staining and goblet cell density (GCD) with the help of impression cytology. Primary outcome measures included post-operative changes in the dry eye indices. Secondary outcome measures included correlation of the dry eye signs and symptoms with various risk factors.
resultsAggravation of both the signs and symptoms of dry eye were noted in immediate post-operative period. The sharp deterioration was followed by a recovering trend towards the end of sixth week. A decrease in GCD was also noted. Risk factors for deterioration include age, duration of exposure to microscope light and effective phacoemulsification time. Diabetic status, socio-economic status and site of incision did not have any effect on dry eye status.
conclusionThere is a transient deterioration of "dry eye" status post-phacoemulsification. The patients should be carefully counselled about the evanescent nature of the disease. Incision can be given at the site of high corneal curvature to neutralize astigmatism without any fear of inducing dry eye. Minimum light exposure and ultrasound energy should be used during the surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.