Evidence map›Paper›PMID 29926275›Full record

ArticleMedical oncology (Northwood, London, England)2018

Racial and geographic disparities in adherence and discontinuation to adjuvant endocrine therapy in Texas Medicaid-insured patients with breast cancer.

Albert J Farias, Wen-Hsing Wu, Xianglin L Du

Abstract read
In one paragraph

Article in Medical oncology (Northwood, London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Albert J FariasDepartment of Preventive Medicine, The Gehr Family Center for Health Systems Science, Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, 2001 N. Soto St, Suite 318B, Los Angeles, CA, 90032, USA. albertfa@usc.edu.ORCID http://orcid.org/0000-0002-6463-7831
Wen-Hsing WuDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
Xianglin L DuDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.

Funding

BEHAVIORAL SCIENCE EDUCATION--CANCER PREVENTION/CONTROLR25CA057712 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MULLEN, PATRICIA DOLAN · 1992 to 2017
$8.6M
Comparative Effectiveness and Cost Effectiveness of Cancer ChemotherapyR01HS018956 · AHRQ · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DU, XIANGLIN · 2012 to 2014
$880k
Agency for Healthcare Research and Quality R01-HS018956AHRQ HHS R01 HS018956Cancer Prevention and Research Institute of Texas RP130051National Cancer Institute R25-CA57712NCI NIH HHS R25 CA057712
6 · The paper itself

Abstract

The purpose of the study is to examine disparities in AET adherence and discontinuation among Texas Medicaid-insured early-stage breast cancer patients. Texas Cancer Registry Medicaid-linked database was used from 2000 to 2007 for breast cancer patients aged 20-64. Multivariable logistic regression was performed to test the association of race/ethnicity and geographic factors with AET adherence and discontinuation. Of the 1240 women with breast cancer, 60.8% of non-Hispanic white vs 46.6% of Black patients were adherent to AET in the first year. After adjusting for confounding, Black patients had lower odds of adherence compared to non-Hispanic white patients (Odds ratio 0.62, 95% CI 0.44-0.87), but they were not more likely to discontinue therapy during the study period. Patients from the Texas/Mexico border had higher odds of adherence compared to other regions (OR 2.32, 95% CI 1.29-4.18). There are substantial racial and geographic disparities in AET adherence and discontinuation among Texas Medicaid-insured women.

Indexed as

MedicaidAdultAntineoplastic Agents, HormonalBreast NeoplasmsChemotherapy, AdjuvantCohort StudiesFemaleHealthcare DisparitiesHumansMedication AdherenceMiddle AgedRacial GroupsRetrospective StudiesTexasUnited StatesYoung AdultAntineoplastic Agents, HormonalAdherenceAETDiscontinuationMedicaidRace/ethnicity

Identifiers

PMID29926275
PMCPMC6038925

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.