Evidence map›Paper›PMID 29925950›Full record

ArticleNature2018

Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation.

Ruby Yu, Xiaoyi Wang, Danesh Moazed

Open access · greenAbstract read
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 128 citations in OpenAlex.

  1. Article
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  16. Article
  17. Challenges and Opportunities Arising from Host-International journal of molecular sciences · 2024
    Review
  18. Review
  19. Review
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ruby YuDepartment of Cell Biology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Xiaoyi WangDepartment of Cell Biology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Danesh MoazedDepartment of Cell Biology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA. danesh@hms.harvard.edu.
Harvard University · USHoward Hughes Medical Institute · US

Funding

RNAi-mediated Targeting of Hetorochromatin AssemblyR01GM072805 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MOAZED, DANESH · 2005 to 2025
$6.9M
Genetics and Genomics PhD Training GrantT32GM096911 · NIGMS · HARVARD MEDICAL SCHOOL · PI KENNEDY, SCOTT G · 2011 to 2020
$2.5M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM072805NIGMS NIH HHS T32 GM096911NIH HHS GM072805
6 · The paper itself

Abstract

Histone post-translational modifications (PTMs) are associated with epigenetic states that form the basis for cell-type-specific gene expression

Indexed as

MethylationRNA InterferenceAllelesCell Cycle ProteinsEpigenomicsFeedback, PhysiologicalGenes, FungalHeterochromatinHistone-Lysine N-MethyltransferaseHistonesLysineMethyltransferasesNuclear ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsCell Cycle Proteinsclr4 protein, S pombeepe1 protein, S pombeHeterochromatinHistone-Lysine N-MethyltransferaseHistonesLysineMethyltransferasesNuclear ProteinsSchizosaccharomyces pombe Proteins

Identifiers

PMID29925950
PMCPMC6312107
OpenAlexW2809116049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.